CEREBROSPINAL FLUID HIV-1 AND COGNITIVE FUNCTION IN PATIENTS RECEIVING THERAPY

接受治疗的患者脑脊液 HIV-1 和认知功能

• 批准号: 7377402
• 负责人: COLIN D HALL
• 金额: $ 1.01万
• 依托单位: UNIV OF NORTH CAROLINA CHAPEL HILL
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-12-01 至 2006-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7377402
• 关键词: CEREBROSPINAL; FLUID; HIV; COGNITIVE; FUNCTION

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The purpose of this observational study is to see how levels of HIV in the blood compare to those in cerebrospinal fluid (CSF), a fluid found around your brain and spinal cord before and after the administration of potent antiretroviral therapy. Also the levels of the different antiretroviral drugs will be measured in the blood and in the CSF and the effects of those drugs will be evaluated. To be in this study, persons also must be participating in an antiretroviral therapy study.

本子项目是利用由NIH/NCRR资助的中心赠款提供的资源的众多研究子项目之一。子项目和研究者（PI）可能已经从另一个NIH来源获得了主要资金，因此可以在其他CRISP条目中表示。列出的机构是中心的，不一定是研究者的机构。这项观察性研究的目的是观察在接受强效抗逆转录病毒治疗前后，血液中的艾滋病毒水平与脑脊液（CSF）中的艾滋病毒水平如何比较。脑脊液是在大脑和脊髓周围发现的液体。不同的抗逆转录病毒药物在血液和脑脊液中的水平也将被测量，这些药物的效果将被评估。参加这项研究的人还必须参加抗逆转录病毒治疗研究。