RACE AND CONTROL OF TISSUE RENIN-ANGIOTENSIN SYSTEM: IDENTIFYING CAUSAL GENES

组织肾素-血管紧张素系统的竞赛和控制：识别致病基因

• 批准号: 7379219
• 负责人: NAOMI D FISHER
• 金额: $ 0.88万
• 依托单位: BRIGHAM AND WOMEN'S HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-04-01 至 2007-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7379219
• 关键词: RACE; CONTROL; TISSUE; RENIN; ANGIOTENSIN

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The purpose of this study is to explain the higher prevalence of high blood pressure and its complications in blacks than in caucasians. The hypothesis to be tested is that blacks have increased activity of the renin-angiotensin system in hormones in their kidneys, which is determined by genetic factors.

该子项目是利用NIH/NCRR资助的中心赠款提供的资源的许多研究子项目之一。子项目和研究者（PI）可能从另一个NIH来源获得主要资金，因此可以在其他CRISP条目中表示。所列机构为中心，不一定是研究者所在机构。这项研究的目的是解释高血压及其并发症在黑人中的患病率高于高加索人。有待检验的假设是，黑人肾脏中的激素中的肾素-血管紧张素系统的活性增加，这是由遗传因素决定的。