COLONY STIMULATING FACTORS IN PATIENTS WITH INTERMITTENT CLAUDICATION

间歇性跛行患者的集落刺激因子

• 批准号: 7376417
• 负责人: ARSHED A QUYYUMI
• 金额: $ 7.49万
• 依托单位: EMORY UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-12-01 至 2006-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7376417
• 关键词: COLONY; STIMULATING; FACTORS; PATIENTS; INTERMITTENT

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This study will evaluate the safety and toxicity of the colony stimulating factor GM-CSF (granulocyte-macrophage colony stimulating factor) in people who have pain in their legs while walking because of blockages in the arteries of their legs. Some individuals are able to naturally grow new blood vessels in an attempt to form bypasses around the blockages. Often these new vessels are inadequate to supply sufficient blood. If it can be safely used, GM-CSF will be used to stimulate new blood vessel growth and relieve symptoms.

本子项目是利用由NIH/NCRR资助的中心赠款提供的资源的众多研究子项目之一。子项目和研究者（PI）可能已经从另一个NIH来源获得了主要资金，因此可以在其他CRISP条目中表示。列出的机构是中心的，不一定是研究者的机构。这项研究将评估集落刺激因子GM-CSF（粒细胞-巨噬细胞集落刺激因子）在因腿部动脉阻塞而行走时腿部疼痛的患者中的安全性和毒性。有些人能够自然地长出新的血管，试图在阻塞周围形成旁路。通常这些新血管不能提供足够的血液。如果可以安全使用，GM-CSF将用于刺激新血管生长和缓解症状。