KIDNEY EARLY EVALUATION PROGRAM (KEEP 30)

本子项目是利用由NIH/NCRR资助的中心赠款提供的资源的众多研究子项目之一。子项目和研究者（PI）可能已经从另一个NIH来源获得了主要资金，因此可以在其他CRISP条目中表示。列出的机构是中心的，不一定是研究者的机构。本研究的主要目的是确定氧化应激标志物是否能前瞻性地预测肾病高危患者尿白蛋白排泄率的升高；并证明超声测量肾容量可以在功能恶化之前预测早期肾单位损失。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The primary aims of this study are to determine if markers of oxidative stress prospectively predict elevations in urinary albumin excretion rate in patients at high risk for kidney disease; and to demonstrate that ultrasonography measurement of renal volume can predict early nephron loss prior to functional deterioration.