ASSESSMENT OF CHANGES IN ABDOMINAL FAT AND METABOLIC AND TISSUE BIOMARKERS DU

本子项目是利用由NIH/NCRR资助的中心赠款提供的资源的众多研究子项目之一。子项目和研究者（PI）可能已经从另一个NIH来源获得了主要资金，因此可以在其他CRISP条目中表示。列出的机构是中心的，不一定是研究者的机构。本研究的目的是确定肥胖患者体重减轻的准确指标，这些指标可用于确定病态肥胖相关疾病风险的降低。患者将接受为期三个月的减肥计划，包括药物或手术干预。体重减轻对人体测量、身体成分和脂肪分布的影响将被确定。身体组成和脂肪分布的变化将被检查它们对肥胖相关疾病的重要风险生物标志物的影响。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The purpose of this study is to identify accurate indicators of weight loss in obese patients that may be utilized to determine the reduction in the associated disease risk from morbid obesity. Patients will undergo a weight loss program over a three-month period, comprising either medical or surgical intervention. The effect of weight loss on anthropormetric measurements, body composition and fat distribution will be determined. Changes in body composition and fat distribution will be examined for their effects on important risk biomarkers for obesity-related disease.