NEUROMUSCULAR CONDITIONING THERAPY FOR DYSSYNERGIC DEFECATION

针对排便失调的神经肌肉调节疗法

• 批准号: 7376982
• 负责人: Satish SC Rao
• 金额: $ 0.03万
• 依托单位: UNIVERSITY OF IOWA
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-03-01 至 2007-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7376982
• 关键词: NEUROMUSCULAR; CONDITIONING; THERAPY; DYSSYNERGIC; DEFECATION

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This multidisciplinary proposal will investigate the efficacy of both standard and innovative, alternative treatments for patients with constipation due to dyssynergic defecation. Constipation affects at least four million Americans, predominantly women and the elderly. It is poorly characterized and inadequately treated. At least 50% of patients with chronic constipation exhibit uncoordinated or dyssynergic defecation. In these patients, biofeedback therapy may improve symptoms. This proposal addresses three broad objectives. The first is to determine if biofeedback therapy is effective in the management of dyssynergic defecation, the second is to investigate the efficacy of home-training and the third is to investigate the psychosocial function and quality of life and the impact of treatment on these parameters.

该子项目是利用NIH/NCRR资助的中心赠款提供的资源的许多研究子项目之一。子项目和研究者（PI）可能从另一个NIH来源获得主要资金，因此可以在其他CRISP条目中表示。所列机构为中心，不一定是研究者所在机构。这项多学科的建议将调查标准和创新的疗效，替代治疗便秘患者由于排便失调。至少有400万美国人受到感染，主要是妇女和老年人。它的特点不明确，治疗也不充分。至少50%的慢性便秘患者表现出排便不协调或不协同。在这些患者中，生物反馈治疗可以改善症状。这项建议涉及三大目标。首先是确定生物反馈治疗是否有效的管理失调排便，第二个是调查家庭训练的疗效，第三个是调查的心理社会功能和生活质量和治疗对这些参数的影响。