General Clinical Research Center

超出空间 但前提是。 大学成人和儿童综合临床研究中心(GCRC)的使命 芝加哥大学的宗旨是为教师提供资源、基础设施和培训，使他们能够出色地开展 翻译研究将治愈疾病并维护所有人的健康。GCRC的目标是 创造一种环境，使这项研究以安全和合乎道德的方式进行。这是我们的 目的促进基础研究人员和临床科学家之间的最佳合作，以将 在替补席上的发现改善了床边的健康。我们的重点领域包括：(1) 了解哮喘、炎症性肠病、心肌病、多囊变的分子基础 卵巢综合征、代谢性骨病和新的甲状腺疾病；(2)诊断、预防和治疗 糖尿病和其他代谢综合征的治疗；(3)物质的治疗和诊断 虐待和压力以及(4)睡眠的生理学和病理学，因为它与肥胖、衰老、怀孕和 其他条件。其他集中的领域包括针对复发性妊娠丢失的新疗法； 治疗肺部疾病和感染性休克。我们提交了来自34个不同调查人员的60个方案(其中20个 他们有NIH的资助)，来自8个不同的专业。我们正在请求支持睡眠和 支持15个协议的时间生物学核心。如果没有GCRC支持，这些协议就不能 已执行。该请求包括一名核心经理和一名0.5FTE睡眠技术员以及设备 进行这些研究所必需的。我们还请求继续支持生物统计学家和 统计遗传学家审查所有方案。该大学为GCRC购买了一台自动DNA 为了跟上我们研究人员要求的大规模基因分型的步伐。我们要求 继续为实验室人员提供支持，以满足这一需求。我们预计将与以下人员一起开发课程 NIH和世界卫生组织将培训来自其他国家的临床领域的科学家 研究。这些要求将使GCRC能够履行其使命，提供最好的 杰出的公益翻译研究。

EXCEED THE SPACE PROVIDED. The mission of the combined adult and pediatric General Clinical Research Center (GCRC) at the University of Chicago is to provide the resources, infrastructure and training for faculty to conduct outstanding translational research which will cure diseases and maintain the health of all people. The GCRC aims to create an environment in which this research is conducted in a safe and ethically sound manner. It is our aim to promote the optimal collaboration among basic researchers and clinical scientists to translate the findings at the bench to improved health at the bedside. Our areas of concentration include: (1) the understanding for the molecular basis for asthma, inflammatory bowel disease, cardiomyopathy,polycystic ovary syndrome, metabolic bone disease and new thyroid diseases; (2) the Diagnosis, Prevention and Treatment of Diabetes Mellitus and other Metabolic Syndromes; (3) Treatment and Diagnosis of Substance Abuse and Stress and (4) Physiology and pathology of sleep as it relates to obesity, ageing, pregnancy and other conditions. Additional areas of concentration include novel treatments for recurrent pregnancy loss; treatment of lung disease and septic shock. We submit 60 protocols from 34 different investigators (20 of whom have NIH funding) from 8 different specialties. We are requesting support for a Sleep and Chronobiology Core that would support 15 protocols. Without GCRC support these protocols cannot be performed. The request includes a core manager and a 0.5 FTE sleep technician as well as equipment necessary to conduct the studies. We are also requesting continued support for the Biostatistician and Statistical Geneticist to review all protocols. The University purchased for the GCRC an automated DNA extractor to keep pace with the large scale genotyping requested by our investigators. We are requesting continued support for laboratory personnel to meet this demand. We anticipate developing a curriculum with the NIH and the World Health Organization to train scientists from other countries in the area of clinical research. Together these requests will allow the GCRC to fulfill its mission of providing the very best in outstanding translational research for the public good.