OUTCOME AFTER SURGICAL CORRECTION OF ANORECTAL MALFORMATIONS

这个子项目是利用由NIH/NCRR资助的中心拨款提供的资源的许多研究子项目之一。子项目和调查员(PI)可能从另一个NIH来源获得了主要资金，因此可能会出现在其他CRISE条目中。列出的机构是针对中心的，而不一定是针对调查员的机构。肛门直肠畸形是一种不常见的先天性缺陷，大约每5000名活产儿中就有一名发生。所有患有这些畸形的患者都有终生的排便问题，因此，可能会遭受严重的社会和身体疾病。虽然已经描述了成人解剖性大便失禁的大便失禁评分系统，但还没有研究在因肛门直肠畸形而导致大便失禁的儿童中开发类似的评分系统。本研究的目的是验证一种新的肛门直肠畸形儿童大便失禁评分系统。接受肛门直肠畸形手术的患者将与两个对照组进行比较：有尿失禁史的儿童和没有尿失禁或大便失禁病史的儿童。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Anorectal malformations are uncommon congenital defects, occurring approximately 1 in 5000 live births. All patients with these malformations have lifelong problems with defecation, and, as a result, can suffer great social and physical morbidity. Although fecal incontinence scoring systems have been described in adults with anatomic fecal incontinence, there have been no studies performed to develop similar scoring systems in children with fecal incontinence due to anorectal malformations. The purpose of this study is to validate a new fecal incontinence scoring system for children with anorectal malformations. Patients who have undergone surgery for anorectal malformations will be compared to two control groups: children with eneuresis and children with no history of urinary or fecal incontinence.