PITUITARY TUMOR SURVEILLANCE: PATHOGENETIC CORRELATION

垂体瘤监测：致病相关性

• 批准号: 7376016
• 负责人: SHLOMO MELMED
• 金额: $ 0.22万
• 依托单位: LUNDQUIST INSTITUTE FOR BIOMEDICAL INNOVATION AT HARBOR-UCLA MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-12-01 至 2006-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7376016
• 关键词: PITUITARY; TUMOR; SURVEILLANCE; PATHOGENETIC; CORRELATION

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This study is a Phase 1, multicenter, open-label, dose-titration of Albutropin in subjects with adult onset growth hormone deficiency. The study is designed to evaluate the safety, tolerability, immunogenicity, pharmacokinetics and pharmacodynamics of difference doses of subcutaneously administered rHA-rHGH in subjects with adult onset growth hormone deficiency.

该子项目是利用NIH/NCRR资助的中心赠款提供的资源的许多研究子项目之一。子项目和研究者（PI）可能从另一个NIH来源获得主要资金，因此可以在其他CRISP条目中表示。所列机构为中心，不一定是研究者所在机构。本研究是一项在成人发作生长激素缺乏症受试者中进行的1期、多中心、开放标签、阿尔布托品剂量滴定研究。本研究旨在评价不同剂量rHA-rHGH皮下给药在成人型生长激素缺乏症受试者中的安全性、耐受性、免疫原性、药代动力学和药效学。