ACUTE&CHRONIC HYPERGLYCEMIC EFFECTS ON MYOGENIC RESPONSE IN HEALTHY & DIABETICS

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This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The purpose of the study was to examine the effects of oral glucose loading (2hr oral glucose tolerance test) on myogenic vasoconstriction in healthy individuals by measuring brachial artery MBV as transmural pressure was altered using an arm tank (- 50 mmHg). We hypothesized that oral glucose loading would be associated with attenuated myogenic vasoconstriction.