STRESS HYPERGLYCEMIA IN EMERGENCY DEPARTMENT (ED) PATIENTS: A NORMAL RESPONSE

这个子项目是利用由NIH/NCRR资助的中心拨款提供的资源的许多研究子项目之一。子项目和调查员(PI)可能从另一个NIH来源获得了主要资金，因此可能会出现在其他CRISE条目中。列出的机构是针对中心的，而不一定是针对调查员的机构。主要目的是确定在急症和血糖升高的急诊室就诊的患者中，有多少人患有未确诊的糖尿病或糖代谢受损。通过评估血糖正常和升高的患者，我们将确定一个可用于识别患糖尿病风险的阈值。第二个目标是确定HbA1c结合ED随机血糖水平是否提高了临床医生区分糖尿病或糖代谢受损与应激性高血糖的能力。我们还将确定，将这些信息与其他容易获得的变量(例如，BMI、年龄、既往病史)结合起来是否会增加糖尿病或糖耐量受损风险分层的精确度。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The main objective is to determine what portion of patients presenting to the ED with acute illness and elevated blood sugar have undiagnosed diabetes or impaired glucose metabolism. By evaluating patients with both normal and elevated blood sugars, we will then determine a threshold that can be used to identify risk of having diabetes. The second objective is to determine whether the HbA1c in combination with the ED random glucose level enhances the clinician's ability to differentiate diabetes or impaired glucose metabolism from 'stress hyperglycemia'. We will also determine whether combining this information with other easily obtained variables (e.g. BMI, age, past medical history) increases the precision of risk stratification for diabetes or impaired glucose tolerance.