GREATER NEW YORK AUTISM CENTER OF EXCELLENCE - CLINICAL CORE

该子项目是利用NIH/NCRR资助的中心赠款提供的资源的许多研究子项目之一。子项目和研究者（PI）可能从另一个NIH来源获得主要资金，因此可以在其他CRISP条目中表示。所列机构为中心，不一定是研究者所在机构。为了响应STAART倡议创建自闭症卓越研究中心的号召，我们提议创建大纽约自闭症卓越研究中心（GNY-ARCE），这将是西奈山医学院，NYSPI/心理卫生研究基金会（NYSPI/RFMH），多伦多大学和北岸长岛犹太卫生系统的合作努力。该中心将融合临床和研究专业知识，以揭示自闭症的潜在机制和治疗方法。其中心目的将是找到核心症状，潜在的神经生物学机制和治疗之间的联系，以更好地了解自闭症综合征，并帮助开发新的和更好的治疗方法。拟议的三个研究项目将通过结合遗传学、功能成像和精神药理学的方法来解决这一问题。STAART卓越中心的另一个目标是通过跨学科合作影响未来的研究，并通过定期举行的一系列会议，会谈和会议注入新的观点。同时，我们致力于向公众传播正在进行的研究和治疗的信息。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. In response to the call of the STAART initiative to create Autism research centers of excellence, we are proposing to create The Greater New York Autism Research Center of Excellence (GNY-ARCE), which will be a collaborative effort of the Mount Sinai School of Medicine, NYSPI/Research Foundation for Mental Hygiene (NYSPI/RFMH), the University of Toronto and North Shore-Long Island Jewish Health System. This center will interweave clinical and research expertise in order to shed new light on the underlying mechanisms and treatment of autism. Its central purpose will be to find links between core symptoms, underlying neurobiological mechanisms and treatments, in order to better understand the syndrome of autism and to aid in the development of new and better treatments. The proposed three research projects will address this issue by combining methodologies from genetics, functional imaging and psychopharmacology. Another goal of the proposed STAART center of excellence will be to influence future research through interdisciplinary collaborations, as well as the infusion of new perspectives through a regular series of meetings, talks and conferences. At the same time, we are committed to disseminate information about ongoing research and treatments to the pu