RESTORATION OF FOREARM AND ELBOW FUNCTION BY FNS

FNS 恢复前臂和肘部功能

• 批准号: 7378090
• 负责人: PATRICK E CRAGO
• 金额: $ 0.66万
• 依托单位: CASE WESTERN RESERVE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-04-01 至 2007-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7378090
• 关键词: RESTORATION; FOREARM; ELBOW; FUNCTION; FNS

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The objective of this work is to investigate methods of maximizing the strength and controllability of stimulated elbow extension for subjects with C5 and C6 spinal cord injuries who have upper extremity neuroprosthesis. We hypothesize that augmenting an established hand grasp neuroprosthesis will give these individuals the ability to grasp and move objects over a greater range of spatial locations and orientations, and improve their ability to perform weight shifts and sliding transfers. The existing hand grasp neuroprosthesis will be augmented by surgical placement of a 16-channel implantable receiver/stimulator (IRS) in the paralyzed triceps in order to restore elbow control in addition to hand grasp/release. Following post-surgical immobilization to allow for adequate healing, subjects will be evaluated for performance of the implanted device, for changes in motor and sensory function, and for functional use of their instrumented hand and arm. The latter will be assessed through use of qualitative and quantitative measures of hand and arm function.

该子项目是利用NIH/NCRR资助的中心赠款提供的资源的许多研究子项目之一。子项目和研究者（PI）可能从另一个NIH来源获得了主要资金，因此可以在其他CRISP条目中表示。所列机构为中心，不一定是研究者所在机构。这项工作的目的是调查的方法，最大限度地提高强度和可控性的刺激肘关节伸展的受试者与C5和C6脊髓损伤上肢神经假体。我们假设，增强现有的手部抓握神经假体将使这些人能够在更大范围的空间位置和方向上抓握和移动物体，并提高他们执行重量转移和滑动转移的能力。现有的手抓握神经假体将通过在麻痹的三头肌中手术放置16通道植入式接收器/刺激器（IRS）来增强，以恢复除手抓握/释放之外的肘部控制。术后固定以充分愈合后，将评价受试者植入器械的性能、运动和感觉功能的变化以及器械手和手臂的功能使用。后者将通过使用手和手臂功能的定性和定量测量进行评估。