IDENTIFICATION OF METAL-ION BINDING PROPERTIES

金属离子结合特性的鉴定

• 批准号: 7381708
• 负责人: ROBERT WEBB
• 金额: $ 4.69万
• 依托单位: UNIVERSITY OF SOUTH DAKOTA
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-05-01 至 2007-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7381708
• 关键词: IDENTIFICATION; METAL; ION; BINDING; PROPERTIES

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. We are interested in the interactions between small peptides and potentially toxic metal ions such as those of zinc, copper, and cadmium. We have developed a screening method which tests random peptides for their ability to bind these metals and measurements to confirm these interactions.

本子项目是利用由NIH/NCRR资助的中心赠款提供的资源的众多研究子项目之一。子项目和研究者（PI）可能已经从另一个NIH来源获得了主要资金，因此可以在其他CRISP条目中表示。列出的机构是中心的，不一定是研究者的机构。我们对小肽与锌、铜和镉等潜在有毒金属离子之间的相互作用感兴趣。我们已经开发了一种筛选方法，测试随机肽结合这些金属的能力，并测量以确认这些相互作用。