MCGs Clinical and Translational Research Transformation

描述（由申请人提供）：本计划拨款申请的目的是促进乔治亚医学院（MCG）制定一项计划，以有效治理、管理和评估临床和转化科学奖（CTSA）的内容和基础。这笔拨款将加强MCG的努力，将该机构的方法转变为临床和转化研究（CTR）。MCG的CTR科学家将重点放在格鲁吉亚死亡的主要原因（包括中风、糖尿病和癌症在内的心血管疾病）上，这些疾病的特点是在服务不足的人口（例如格鲁吉亚农村人口）和少数民族，特别是非洲裔美国人之间存在巨大的健康差距。研究人员来自多个学科（遗传学、生物信息学、生物统计学和流行病学、健康行为、生理学、分子和细胞生物学、药理学、临床医学和远程医疗），横跨所有5个学院（医学、牙科、护理、联合健康科学和研究生院）。为了提高将科学发现转化为医疗保健的效率和速度，并培养一支训练有素的生物医学CTR科学家骨干队伍，MCG领导层已开始建立一种环境，为参与CT科学、教育和培训学科提供基础设施、资源和全机构支持。这种转变将有助于使格鲁吉亚唯一的公共卫生科学大学完成其消除健康差距和改善格鲁吉亚人健康的使命，成为未来医学的前沿，我们设想的是预防，预测和个性化。每个学科和所有5所学院的代表组成的工作组将解决4个主要的具体目标：1)基于MCG的点击率优势，我们在点击率和相关职业培训和教师发展方面的增长机会是什么？2)在MCG现有资源、服务和技术的基础上，我们需要什么才能成功转型为多学科、跨学科的CTR？3)新CTR学术之家的最佳组织结构是什么？如何对其进行治理和评价？4)为了促进点击率的转变，MCG正在投入和需要投入哪些资源？所有学校强有力的高层领导支持，每两周一次的工作组会议和外部咨询意见将确保目标的实现，从而在3年内实现CTSA。

DESCRIPTION (provided by applicant): The objective of this planning grant application is to facilitate Medical College of Georgia's (MCG) development of a plan for the content of and foundation for effective governance, administration and evaluation of a Clinical and Translational Science Award (CTSA). This grant will enhance MCG's efforts to transform the institution's approach to clinical and translational research (CTR). MCG's CTR scientists are focused upon the leading causes of mortality in Georgia (cardiovascular diseases including stroke, diabetes and cancer) which are characterized by significant health disparities among under served populations (e.g., rural Georgians) and ethnic minorities, especially African-Americans. Researchers represent multiple disciplines (genetics, bioinformatics, biostatistics and epidemiology, health behavior, physiology, molecular and cellular biology, pharmacology, clinical medicine and telemedicine) & span all 5 schools (Medicine, Dentistry, Nursing, Allied Health Sciences, and Graduate School). To enhance efficiency and speed of translating scientific discoveries into health care and develop a cadre of well-trained biomedical CTR scientists, MCG leadership has initiated the process of establishing an environment that will provide infrastructure, resources and institution-wide support for participation in the discipline of CT science, education and training. This transformation will help enable Georgia's only Public Health Science University accomplish its mission of eliminating health disparities and improving the health of Georgians by being at the fore front of future medicine, which we envision as being preventive, predictive and personalized. Working groups with representatives from each discipline and all 5 schools will address 4 primary specific aims: 1)Building upon MCG's CTR strengths, what are our opportunities for growth in CTR and associated career training and faculty development?; 2) Building upon MCG's available resources, services and technologies, what is needed to enable our successful transformation into multi- and inter-disciplinary CTR?; 3) What will be the optimum organizational structure of the new CTR academic home and how will it be governed and evaluated?; 4) What resources is MCG committing and will need to commit to facilitate the CTR transformation? Strong senior leadership support across all schools, bi-weekly meetings of working groups and external advisory input will ensure accomplishment of the aims, leading to a CTSA within 3 years.