COBRE: LSU HSC: ADMINISTRATIVE CORE

COBRE：LSU HSC：行政核心

• 批准号: 7382067
• 负责人: Stephen M. Lanier
• 金额: $ 39.3万
• 依托单位: LSU HEALTH SCIENCES CENTER
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-07-01 至 2007-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7382067
• 关键词: COBRE; LSU; HSC; ADMINISTRATIVE; CORE

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The administrative core is based in the Department of Pharmacology and supports the overall management of the program. The administrative core provides the umbrella for effective operation of the program. The Program Director, Stephen M. Lanier, Ph.D. is responsible for all administrative aspects of the program and oversight of the mentoring effort. Lynnette Small serves as Administrative Coordinator for the COBRE grant and works very closely with the Department of Pharmacology Business Manager, Karen Jorgenson. Ms. Small has established a superb office that handles all fiscal, purchasing, and organizational issues for the COBRE administrative core. She meets monthly with each of the Junior Investigators and Core Directors and weekly with the Program Director, Dr. Lanier. Ms. Small has also worked very closely with our departmental Personnel Director, Mr. Paul Lam, to bring on new staff. Three established faculty joined us as new mentors on the COBRE. Dr. Parthasarathy joined us from Emory University and Dr. Lucchesi joined us from the University of Alabama - Birmingham. Dr. Kapusta is a Professor in the Department of Pharmacology with two R01 grants focused on the role of opioid peptides on control of cardiovascular and renal function. Drs. Lucchesi and Parthasarathy are well funded by multiple grants from NIH and work in the area of vascular biology and/or cardiac hypertrophy. Projects, Directors and Mentors are listed below: Project 1 - PARP1 and Oxidant Stress in the Vasculature Project Director/Mentored JI: Hamid A. Boulares, Ph.D. Mentor: Sampath Parthasarathy, Ph.D. Project 2 - Gene Transfer, Oxidant Stress, and Diabetic Vascular Disease Project Director/Mentored JI: Frank Park, Ph.D. Mentor: Daniel R. Kapusta, Ph.D. Project 3 - Integration of Growth Factors and Integrin Signaling in VSMC Project Director/Mentored JI: Andrew D. Catling, Ph.D. Mentor: Pamela A. Lucchesi, Ph.D. Project 4 - ER to GOLGI Trafficking of Signaling Proteins in Cardiac Myocytes and VSMC Project Director/Mentored JI: Guangyu Wu, Ph.D. Mentors: William Claycomb, Ph.D. and Stephen M. Lanier, Ph.D. Project 5 - Vascular smooth muscle plasticity in nitric oxide deficiency Project Director/Mentored JI: Gregory M. Dick, Ph.D. Mentors: William M. Chilian, Ph.D. and Daniel R. Kapusta, Ph.D. Project 6 - Role of Inflammation in Endothelial Reperfusion Injury Project Director/Mentored JI: Cuihua Zhang, Ph.D. Mentor: William M. Chilian, Ph.D. The administrative support team assisted in the development of two shared instrumentation grants submitted in March 2005, as well as an NIH institutional predoctoral training grant, submitted in September 2004, for "Training in Integrative Pharmacological and Physiological Sciences". These initiatives will directly benefit the developing program in cardiovascular biology. NIH/NCRR Shared Instrumentation Grant "Thermo Finnigan Proteome X LTQ Workstation (LC/MS) with IBM e-server computer" PI: Art L. Haas, Ph.D. Project Period: 04/01/2006 - 03/31/2007 Total Cost: $496,150 Submitted: March 21, 2005 NIH/NCRR Shared Instrumentation Grant "In Vivo Electron Paramagnetic Resonance Imaging System (Bruker Elesys)" PI: Barry Potter, Ph.D. Project Period: 04/01/2006 - 03/31/2007 Total Cost: $482,170 Submitted: March 21, 2005 NIH/NIGMS Predoctoral Training Grant "Training in Integrative Pharmacological and Physiological Sciences" PI: Stephen M. Lanier, Ph.D. Project Period: 07/01/2005 to 06/30/2010 Total Costs: $865,353 The administrative core also established the WEB site for the LSUHSC Cardiovascular Center of Excellence and for the COBRE program "Mentoring in Cardiovascular Biology". http://www.medschool.lsuhsc.edu/cardio_center/ http://www.medschool. suhsc.edu/cardio_center/COBRE.asp In the upcoming year, we will be providing continued support for grant development by Junior Investigators, Shared Instrumentation Awards and grants for infrastructure development and upgrade of animal care facilities. This core is functioning fine and no changes are anticipated in the upcoming year.

该子项目是利用NIH/NCRR资助的中心赠款提供的资源的许多研究子项目之一。子项目和研究者（PI）可能从另一个NIH来源获得主要资金，因此可以在其他CRISP条目中表示。所列机构为中心，不一定是研究者所在机构。行政核心设在药理学系，并支持该计划的整体管理。行政核心为方案的有效运作提供了保护伞。项目总监Stephen M. Lanier博士负责该计划的所有行政方面，并监督指导工作。Lynnette Small担任COBRE赠款的行政协调员，并与药理学业务经理Karen Jorgenson密切合作。斯莫尔女士建立了一个一流的办公室，处理COBRE行政核心的所有财务、采购和组织问题。她每月与初级研究员和核心主任会面，每周与项目主任拉尼尔博士会面。Small女士还与我们的部门人事总监Paul Lam先生密切合作，以引进新员工。 三个既定的教师加入我们作为新的导师在眼镜蛇。Parthasarathy博士来自埃默里大学，Lucchesi博士来自亚拉巴马大学-伯明翰分校。Kapusta博士是药理学系的教授，拥有两项R 01赠款专注于阿片肽对心血管和肾功能控制的作用。 Lucchesi和Parthasarathy博士得到了NIH的多赠款，并在血管生物学和/或心脏肥大领域工作。 项目，主任和导师如下所列：项目1 -PARP 1和氧化应激在血管项目主任/指导JI：哈米德A. Boulares博士导师：Sampath Parthasarathy博士 项目2 -基因转移，氧化应激和糖尿病血管疾病项目主任/指导JI：Frank Park，博士导师：丹尼尔R。Kapusta博士 项目3 -VSMC中生长因子和整合素信号的整合项目总监/指导JI：Andrew D. Catling博士导师：Pamela A. Lucchesi博士 项目4 -心肌细胞和VSMC中ER至GOLGI的信号蛋白运输项目负责人/导师JI：Guangyu Wu，Ph.D.导师：William Claycomb博士Stephen M. Lanier博士 项目5 -一氧化氮缺乏症中的血管平滑肌可塑性项目主任/指导JI：Gregory M. Dick博士导师：William M. Chilian博士和丹尼尔R. Kapusta博士 项目6 -炎症在内皮再灌注损伤中的作用项目负责人/导师：张翠华博士导师：William M. Chilian博士 行政支助小组协助开发了2005年3月提交的两项共享仪器赠款，以及2004年9月提交的国家卫生研究院机构博士前培训赠款，用于“综合药理学和生理科学培训”。 这些举措将直接有利于心血管生物学的发展计划。 NIH/NCRR共享仪器资助“Thermo Finnigan Proteome X LTQ工作站（LC/MS）与IBM电子服务器计算机”PI：Art L。哈斯博士项目周期：04/01/2006 - 03/31/2007总成本：$496，150提交时间：2005年3月21日NIH/NCRR共享仪器资助“体内电子顺磁共振成像系统（Bruker Elesys）”PI：巴里波特博士项目周期：04/01/2006 - 03/31/2007总费用：$482，170提交：2005年3月21日NIH/NIGMS博士前培训补助金“综合药理学和生理科学培训”PI：Stephen M. Lanier博士项目周期：2005年1月7日至2010年6月30日总费用：865，353美元行政核心还为LSUHSC心血管卓越中心和COBRE计划“心血管生物学指导”建立了网站。http://www.medschool.lsuhsc.edu/cardio_center/ http：//www.medschool. suhsc.edu/cardio_center/COBRE.asp在即将到来的一年里，我们将继续支持初级研究人员的赠款开发，共享仪器奖以及基础设施开发和动物护理设施升级的赠款。这一核心运作良好，预计来年不会发生变化。