SAN DIEGO LATINO RESEARCH CENTER OF EXCELLENCE PARTNERSHIP TO REDUCE CVD DISPARIT

圣地亚哥拉丁裔卓越研究中心合作减少 CVD 差异

• 批准号: 7351946
• 负责人: Gregory A Talavera
• 金额: $ 119.17万
• 依托单位: SAN DIEGO STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-09-30 至 2012-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7351946
• 关键词: Adherence; American; Ancillary Study; Behavioral; Blood specimen; California; Cardiovascular Diseases; Caring; Centers of Research Excellence; Cholesterol; Clinical; Collaborations; Communities; Community Health; Community Health Centers; Cross-Sectional Studies; Diabetes Mellitus; Disadvantaged; Disease Outcome; Education; Elements; Guidelines; Health; High Density Lipoproteins; Hispanics; Information Systems; Intervention; Intervention Studies; Knowledge; Lateral; Latino; Life; Life Style; Lipids; Low income; Measures; Medial; Mentors; Methods; Minority; Modeling; Morbidity - disease rate; Nested Case-Control Study; Outcome; Patients; Planning Techniques; Population; Primary Health Care; Public Health Schools; Randomized Clinical Trials; Research; Research Design; Research Methodology; Research Personnel; Research Training; Risk; Risk Factors; Score; Self Management; Serum; Services; System; Testing; Theoretical model; Therapeutic; Thick; Training; Training Programs; United States Health Resources and Services Administration; Universities; Weight; base; cardiovascular disorder risk; cohort; cysteine rich protein; design; energy balance; experience; gene environment interaction; genetic risk factor; health disparity; improved; innovation; interest; medical schools; programs

SAN DIEGO LATINO RESEARCH CENTER OF EXCELLENCE: PARTNERSHIP TO REDUCE CVD DISPARITIES IN LATINOS The San Diego Latino Research Center of Excellence is a tri-lateral collaboration that seeks to promote and expedite research that improves diabetes and cardiovascular disease outcomes in low-income Latinos living in the border region of San Diego. San Diego State University (SDSU) and the University of California, San Diego (UCSD) represent two large research intensive universities, one with a school of public health and the other with a school of medicine but both with experience and interest in community based research and training. The San Ysidro Health Center (SYHC) is a large, predominantly Latino-serving community health center that provides services to disadvantaged patients and also has a research center. SYHC is mandated by the Health Resources and Service Administration (HRSA) to engage in the Federal Initiative called the Health Disparities Collaborative (HOC). The HOC uses the methodology of the Planned Care Model and the Model for Improvement in the context of Community Oriented Primary Care to make a positive difference in the lives of hundreds of thousands of Americans (BPCHC, 2006). The San Diego Latino Research Center of Excellence proposes to focus on the disparities in diabetes and cardiovascular disease (CVD) and its associated bio-behavioral risk factors experienced by low-income Latinos living in the San Diego border region. The main research plan proposes a randomized clinical trial evaluating the efficacy of 2 culturally appropriate methods for applying the National Cholesterol Education Program (NCEP, 2001) and the American Diabetes Association (ADA, 2001) guidelines. The focus of the intervention methods includes strategies that patient self management, delivery system design, clinical information systems and decision support, all key elements of the HDC Planned Care Model. Innovations include the use of bilingual Community Health Workers, environmental assessments for barriers to adherence, culturallyappropriate behavioral strategies based on a theoretical model and the use of carotid intimal medial thickness (CIMT) as the primary outcome in a predominantly Latino cohort. Integrated into the intervention research design is the capacity for CVD cross-sectional studies, for example, identification of genetic risk factors and gene-environment interactions specific to the Latino population, nested case-control studies and banked serum to attract new investigators and expand the scientific capacity of the proposal. The training core plan proposes a training program that focuses on the existing training programs and the strengths of each partner. SDSU and UCSD will supply the training and mentoring in research methods for minority investigators interested in CVD disparities research and non-minority investigators interested in health disparities. The SYHC will provide the population of focus and the setting for disparities research and the clinicians with intimate knowledge of the Latino community.

圣地亚哥拉丁裔卓越研究中心：合作减少 CVD 拉丁美洲人的差异 圣地亚哥拉丁裔卓越研究中心是一个三边合作项目，旨在促进 并加快改善低收入拉丁裔糖尿病和心血管疾病结果的研究 居住在圣地亚哥边境地区。圣地亚哥州立大学 (SDSU) 和加州大学， 圣地亚哥大学 (UCSD) 代表两所大型研究密集型大学，其中一所设有公共卫生学院， 另一个拥有医学院，但对社区研究有经验和兴趣， 训练。圣伊西德罗健康中心 (SYHC) 是一个大型的、主要为拉丁裔提供服务的社区健康中心 中心为弱势患者提供服务，并设有一个研究中心。 SYHC 的授权是 卫生资源和服务管理局 (HRSA) 参与名为“健康”的联邦倡议 差异协作（HOC）。 HOC 使用计划护理模型和模型的方法 改善面向社区的初级保健，为人们的生活带来积极的改变 数十万美国人（BPCHC，2006）。 圣地亚哥拉丁裔卓越研究中心建议重点关注糖尿病和糖尿病患者之间的差异 低收入拉丁美洲人经历的心血管疾病（CVD）及其相关的生物行为危险因素 居住在圣地亚哥边境地区。主要研究计划提出一项随机临床试验评估 应用国家胆固醇教育计划的 2 种适合文化的方法的功效 （NCEP，2001）和美国糖尿病协会（ADA，2001）指南。干预重点 方法包括患者自我管理、输送系统设计、临床信息系统的策略 和决策支持，HDC 计划护理模型的所有关键要素。创新包括使用 双语社区卫生工作者，针对依从性障碍的环境评估，文化适宜性 基于理论模型和颈动脉内膜中层厚度的行为策略 （CIMT）作为以拉丁裔为主的队列的主要结果。融入干预研究 设计是CVD横断面研究的能力，例如识别遗传风险因素和 拉丁裔人群特有的基因-环境相互作用、巢式病例对照研究和库存血清 吸引新的研究人员并扩大该提案的科学能力。 培训核心计划提出了一个培训计划，重点关注现有培训计划和 每个合作伙伴的优势。 SDSU 和 UCSD 将提供研究方法方面的培训和指导 对 CVD 差异研究感兴趣的少数族裔研究人员和对健康感兴趣的非少数族裔研究人员 差异。 SYHC 将为差异研究和研究提供重点人群和环境 对拉丁裔社区有深入了解的临床医生。