RESISTIVE TRAINING AND CHROMIUM PICOLINATE: EFFECTS ON INOSITOLS AND LIVER

抗阻训练和吡啶甲酸铬：对肌醇和肝脏的影响

• 批准号: 7355263
• 负责人: W W CAMPBELL
• 金额: $ 0.29万
• 依托单位: WASHINGTON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-02-01 至 2007-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7355263
• 关键词: RESISTIVE; TRAINING; CHROMIUM; PICOLINATE; EFFECTS

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Resistive Training and Chromium Picolinate: Effects on Inositols and Liver and Kidney Functions in Older Adults: This study assessed the effects of resistive training (RT) with or without chromium picolinate (Cr-pic) supplementation on the 24-h urinary excretions of myo-inositol, D-chiro-inositol, and pinitol, as well as clinical indices of kidney and liver functions. Thirty-two nondiabetic subjects, age 62 ¿ 4 y, performed RT twice weekly for 12 wk and consumed either 924 ¿g Cr/d as Cr-pic (n = 17) or a placebo (n = 15). Whole-body strength increased in all subjects by 20% and urinary chromium excretion increased 47-fold in the Cr-pic group. Urinary myo-inositol, D-chiro-inositol, and pinitol were not changed with RT or influenced by Cr-pic. Serum indices of kidney and liver functions were within clinically normal ranges at baseline and the end of the study. These results suggest that RT did not influence the urinary excretions of inositols. High dose Cr-pic did not influence the urinary excretion of inositols and the selected indices of kidney and liver functions in conjunction with RT.

该子项目是利用NIH/NCRR资助的中心赠款提供的资源的许多研究子项目之一。子项目和研究者（PI）可能从另一个NIH来源获得主要资金，因此可以在其他CRISP条目中表示。所列机构为中心，不一定是研究者所在机构。抗阻训练和吡啶甲酸铬：对老年人肌醇和肝肾功能的影响：本研究评估了抗阻训练（RT）与或不与吡啶甲酸铬（Cr-pic）补充对24小时尿中肌醇，D-手性肌醇和松醇排泄的影响，以及肾和肝功能的临床指标。32名非糖尿病受试者，年龄62 - 4岁，每周两次进行RT，持续12周，并以Cr-pic（n = 17）或安慰剂（n = 15）形式消耗924-g Cr/d。在所有受试者中，全身力量增加了20%，尿铬排泄量增加了47倍。尿肌醇、D-手性肌醇和松醇不随RT而变化，也不受Cr-pic的影响。基线和研究结束时，肾和肝功能的血清指数均在临床正常范围内。这些结果表明，RT不影响尿中肌醇的排泄。高剂量铬-pic对尿肌醇排泄量及肾、肝功能指标无影响。