SPECIFICITY OF HISTONE ACETYLTRANSFERASE ENZYMES FROM ARABIDOPSIS THALIANA

拟南芥组蛋白乙酰转移酶的特异性

• 批准号: 7355309
• 负责人: CRAIG Stuart PIKAARD
• 金额: $ 1.4万
• 依托单位: WASHINGTON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-02-01 至 2007-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7355309
• 关键词: SPECIFICITY; HISTONE; ACETYLTRANSFERASE; ENZYMES; ARABIDOPSIS

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Mass spectrometry is used to determine which amino acid residues on H3 and H4 histones are acetylated by various histone acetyl transferases found in Arabidopsis thaliana. The goal is to determine the specificity and the degree to which the subtrates are modified.

该子项目是利用NIH/NCRR资助的中心赠款提供的资源的许多研究子项目之一。子项目和研究者（PI）可能从另一个NIH来源获得主要资金，因此可以在其他CRISP条目中表示。所列机构为中心机构，不一定为研究者机构。质谱法用于确定H3和H4组蛋白上的哪些氨基酸残基被拟南芥中发现的各种组蛋白乙酰基转移酶乙酰化。目的是确定特异性和修饰的程度。