CORE--IMAGING FACILITY

核心——成像设备

• 批准号: 6824709
• 负责人: RABI TAWIL
• 金额: $ 29.83万
• 依托单位: UNIVERSITY OF ROCHESTER
• 依托单位国家: 美国
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-09-30 至 2008-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6824709
• 关键词: biomedical facility; confocal scanning microscopy; cooperative study; electron microscopy; fluorescent in situ hybridization; immunocytochemistry; microscopy; muscular dystrophy

Microscopic imaging techniques will be used extensively in all of the proposed MDCRC scientific projects. The purpose of the Muscular Dystrophy Imaging Core is to insure that the proposed scientific projects have facilitated access to the various imaging techniques needed to fulfill their stated aims. This will be accomplished by significantly increasing the imaging capabilities of the Neuromuscular Disease Center's Neuromuscular Pathology Laboratory. In addition, the existing expertise of the Laboratory in handling muscle tissue will be combined to those available in established imaging cores within the institution. The Core will provide access to: 1) specialized muscle histochemical and immunohistochemical techniques, 2) fluorescent in situ hybridization (FISH), 3) confocal microscopy and 4) electron microscopy. Expertise will also be available within the cores to help Center investigators apply other techniques, whose need may arise during the conduct of the proposed studies.

显微成像技术将广泛用于所有拟议的MDCRC科学项目。肌营养不良成像核心的目的是确保拟议的科学项目促进获得实现其既定目标所需的各种成像技术。这将通过显著提高神经肌肉疾病中心神经肌肉病理学实验室的成像能力来实现。此外，该实验室在处理肌肉组织方面的现有专门知识将与该机构内已建立的成像核心的现有专门知识相结合。该核心将提供：1）专门的肌肉组织化学和免疫组织化学技术，2）荧光原位杂交（FISH），3）共聚焦显微镜和4）电子显微镜。中心还将提供专业知识，以帮助中心研究人员应用可能需要的其他技术 在进行拟议研究期间。