High blood pressure and gut microbiota: mechanisms and therapeutic potential

高血压和肠道微生物群：机制和治疗潜力

• 批准号: nhmrc : GNT1159721
• 金额: $ 80.65万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2019
• 资助国家: 澳大利亚
• 起止时间: 2019-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/high-blood-pressure-therapeutic-potential/1379088
• 关键词: blood; pressure; gut; microbiota; mechanisms

Evidence from our group has emerged that the association between fibre intake and lower blood pressure may be due to our gut bacteria. While our bodies are incapable of digesting some types of fibre, they feed the community of ‘good’ bacteria, resulting in the release of short-chain fatty acids. These might be beneficial in lowering our blood pressure. Our aim is to establish the role of the gut bacteria and short-chain fatty acids in the development and treatment of hypertension.

来自我们小组的证据表明，纤维摄入量和低血压之间的联系可能是由于我们的肠道细菌。虽然我们的身体无法消化某些类型的纤维，但它们会喂养“好”细菌，导致短链脂肪酸的释放。这些可能有助于降低我们的血压。我们的目的是确定肠道细菌和短链脂肪酸在高血压的发展和治疗中的作用。