HEART RATE RECOVERY AFTER EXERCISE DYNAMICAL ANALYSIS

运动后心率恢复动态分析

• 批准号: 7366514
• 负责人: STUART D KATZ
• 金额: $ 0.81万
• 依托单位: BETH ISRAEL DEACONESS MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-03-01 至 2007-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7366514
• 关键词: HEART; RATE; RECOVERY; AFTER; EXERCISE

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Impaired heart rate recovery immediately after exercise has been reported to be an important, independent marker of risk. However, the optimal measures of heart rate recovery have not been determined. We are systematically comparing the ability of conventional and newer dynamical measures of heart rate recovery in different groups of subjects with heart disease as well as healthy controls. The first investigation in this project involves analysis of exercise test data from subjects with congestive heart failure in a trial of pyridostigmine, a drug which increases vagal tone. This collaborative work is supported in part by the American Heart Association, the NHLBI and the NCRR/GCRC.

这个子项目是利用由NIH/NCRR资助的中心拨款提供的资源的许多研究子项目之一。子项目和调查员(PI)可能从另一个NIH来源获得了主要资金，因此可能会出现在其他CRISE条目中。列出的机构是针对中心的，而不一定是针对调查员的机构。据报道，运动后即刻心率恢复受损是一个重要的、独立的风险标志。然而，心率恢复的最佳措施尚未确定。我们正在系统地比较不同心脏病受试者和健康对照组中传统和新的动态心率恢复措施的能力。该项目的第一个调查包括对充血性心力衰竭患者的运动试验数据进行分析，该试验是一种增加迷走神经张力的药物。这项合作工作得到了美国心脏协会、NHLBI和NCRR/GCRC的部分支持。