Interactive CD-ROM on Cancer Genetics for Hispanics

西班牙裔癌症遗传学互动 CD-ROM

• 批准号: 7489023
• 负责人: Susan K Peterson
• 金额: $ 43.28万
• 依托单位: UNIVERSITY OF TX MD ANDERSON CAN CTR
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-09-15 至 2012-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7489023
• 关键词: Address; Attitude; Awareness; Behavior; Breast; Breast Cancer Genetics; CD-I; CD-ROM; Caring; Characteristics; Clinical; Communities; Community Health; Computers; Condition; Conflict (Psychology); Consult; Counseling; Data; Decision Making; Depth; Development; Disease; Educational Intervention; Educational Materials; Effectiveness; Effectiveness of Interventions; Elements; Evaluation; Family history of; Focus Groups; Future; Gene Mutation; Genetic Counseling; Genetic Services; Genetic screening method; Genetic testing for cancer risk; Geographic Locations; Goals; Health; Health Personnel; Health Promotion; Health Services; Health education; Healthcare; Hereditary Malignant Neoplasm; Heredity; Hispanics; Individual; Inherited; Intervention; Intervention Studies; Interview; Knowledge; Life; Malignant Neoplasms; Malignant neoplasm of ovary; Measures; Methods; Mexico; Modeling; Modification; Outcome; Participant; Phase; Process; Program Effectiveness; Purpose; Qualitative Methods; Quality of life; Randomized; Randomized Controlled Clinical Trials; Recording of previous events; Recruitment Activity; Relative (related person); Research; Research Personnel; Resources; Review Literature; Risk; Risk Assessment; Risk Factors; Sampling; Score; Services; Staging; Standards of Weights and Measures; Subgroup; Testing; Texas; Training; Update; Upper arm; Urination; Woman; Writing; base; behavior test; cancer genetics; cancer risk; computer program; design; experience; health organization; improved; innovation; insight; malignant breast neoplasm; programs; satisfaction

DESCRIPTION (provided by applicant): Background: There is a growing awareness of family history as a risk factor for disease and the availability of genetic testing for inherited cancers continues to increase. However, effective, efficient resources for educating individuals about inherited cancer risk are lacking, especially in geographic areas that are underserved by genetics services. In particular, there is a dearth of educational resources for Hispanics on cancer genetics that are both culturally relevant and available in Spanish. The broad, long-term objective is to improve Hispanic women's understanding about breast cancer risk by demonstrating the effectiveness of an interactive computer program as an effective and sustainable educational resource. Aims: We propose to first modify and adapt an effective, interactive computer-based program, "Breast Cancer Risk and Genetic Testing," to be culturally and linguistically appropriate for Hispanic. Second, we propose to conduct a randomized, controlled evaluation of the modified computer program when used alone vs. when guided by a trained promotora, or lay health worker. Methods: Qualitative methods will be used to identify changes and modifications to the current computer program to make it more culturally relevant. The modified program will be created in both English and Spanish. Focus groups consisting of Hispanic women with a prior history of breast cancer as well as those with a family history of the disease will be conducted, along with key informant interviews and expert panel reviews. Following the modification and adaptation of the program for a Hispanic audience, we will recruit women from a community-based health organization for participation in a randomized trial to evaluate the effectiveness of the program. Women will be randomized to use the program under the guidance of a trained lay health worker, or promotora, or to use the program unassisted. Main outcomes, including knowledge, perceived risk, decisional satisfaction, use of health care services, and satisfaction with the intervention, will be measured immediately following the intervention, and at 1 and 6 months post-intervention. Relevance: Effective, efficient resources for educating individuals about inherited cancer risk are lacking, especially in geographic areas that are underserved by genetics services. In particular, there is a dearth of educational resources for Hispanics on cancer genetics that are both culturally relevant and available in Spanish. This study will use an innovative application of two effective and acceptable health education and health promotion methods to address the needs of Hispanic women living in a geographic area that is underserved in terms of genetics services. In doing so, we will address an important educational void by providing the information women need in a manner that is satisfying, acceptable and effective.

描述（由申请人提供）： 工作背景：人们越来越认识到家族史是疾病的一个危险因素，遗传性癌症的基因检测也在不断增加。然而，缺乏有效、高效的资源来教育个人了解遗传性癌症的风险，特别是在遗传学服务不足的地理区域。特别是，西班牙裔人缺乏与文化相关且可用西班牙语的癌症遗传学教育资源。广泛的，长期的目标是通过展示交互式计算机程序作为有效和可持续的教育资源的有效性，提高西班牙裔妇女对乳腺癌风险的理解。 目标：我们建议首先修改和适应一个有效的，互动的基于计算机的程序，“乳腺癌风险和基因检测”，是文化和语言适合西班牙裔。其次，我们建议对修改后的计算机程序单独使用与在训练有素的推广人或非专业卫生工作者指导下使用进行随机、对照评估。 方法：定性方法将被用来识别当前计算机程序的变化和修改，使其更具文化相关性。修改后的程序将以英语和西班牙语创建。焦点小组包括西班牙裔妇女与乳腺癌的既往史以及那些与家族史的疾病将进行，沿着与关键的线人访谈和专家小组审查。在为西班牙裔观众修改和调整该计划后，我们将从社区卫生组织招募妇女参加随机试验，以评估该计划的有效性。妇女将被随机分配在经过培训的非专业卫生工作者或推广人的指导下使用该计划，或在没有帮助的情况下使用该计划。主要结果，包括知识，感知风险，决策满意度，医疗保健服务的使用，以及对干预的满意度，将在干预后立即测量，并在干预后1个月和6个月。 相关性：缺乏有效、高效的资源来教育个人了解遗传性癌症的风险，特别是在遗传学服务不足的地理区域。特别是，西班牙裔人缺乏与文化相关且可用西班牙语的癌症遗传学教育资源。这项研究将采用两种有效和可接受的健康教育和健康促进方法的创新应用，以解决生活在遗传服务不足的地理区域的西班牙裔妇女的需求。在这样做时，我们将以令人满意、可接受和有效的方式提供妇女所需的信息，从而填补一个重要的教育空白。