HIV latency, pathogenesis and immunity

HIV潜伏期、发病机制和免疫

• 批准号: nhmrc : 1052979
• 负责人: Prof Anthony Kelleher
• 金额: $ 882.36万
• 依托单位: The University of New South Wales
• 依托单位国家: 澳大利亚
• 项目类别: Program Grants
• 财政年份: 2014
• 资助国家: 澳大利亚
• 起止时间: 2014-01-01 至 2018-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/hiv-latency-pathogenesis-immunity/112307
• 关键词: HIV; latency; pathogenesis; immunity

The development of cures, vaccines and better treatments for HIV/AIDS is an urgent global health priority. This team of seven groups in Sydney and Melbourne will study how HIV can lie dormant in some parts of the body, evading eradication by HIV therapy, as well as how the immune system responds to the virus. This will allow for design of novel vaccines and treatments. The researchers have skills in basic virology and immunology, and translating laboratory findings into human clinical trials.

研制艾滋病毒/艾滋病的治疗方法、疫苗和更好的治疗方法是一项紧迫的全球卫生优先事项。这个由悉尼和墨尔本的七个小组组成的小组将研究艾滋病毒如何在身体的某些部位潜伏，逃避艾滋病毒治疗的根除，以及免疫系统如何对病毒作出反应。这将允许设计新的疫苗和治疗方法。研究人员具有基础病毒学和免疫学的技能，并将实验室发现转化为人类临床试验。