P-30 Core Grant for Vision Research

P-30 视觉研究核心补助金

基本信息

  • 批准号:
    7413481
  • 负责人:
  • 金额:
    $ 16.21万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2002
  • 资助国家:
    美国
  • 起止时间:
    2002-04-01 至 2009-03-31
  • 项目状态:
    已结题

项目摘要

The proposed Core facilities are designed to enhance and make more efficient the NEI-supported research carried out at the Massachusetts Eye and Ear Infirmary. The participating investigators conduct research primarily involving the retina, retinal diseases, glaucoma, and ocular development. The proposed Core is organized into the following four modules. 1. The Morphology Module provides resources, services, training, and technical assistance for investigators who require laser scanning confocal microscopy, transmission electron microscopy, light microscopy, immunofluorescence analysis, and related technologies. 2. The Molecular Biology Module provides services and equipment and DMA sequencing currently required for state-of-the-art molecular biology experiments involving vision science. 3. The Clinical Interface Module provides investigators with centralized and efficient processing of blood and other types of samples derived from patients who volunteer to participate in molecular genetics research and other research of the participating investigators. As such, it serves as the interface between clinicians who diagnose and treat patients with ocular disease and the clinician-scientists and basic scientists who wish to conduct experiments that require the analysis of DMA or other biological compounds derived from those patients. 4. A newly proposed module is the In Vivo Imaging and Function Module. It will use non-invasive techniques to evaluate the status of ocular tissues in living animals used in vision research. The two technologies to be initially offered by this module will be optical coherence tomographic (OCT) imaging and electroretinographic (ERG) evaluation of retinal function. These methods will allow investigators to follow the course of ocular disease over time in individual animals, thereby reducing the number of animals needed for vision research as well as providing new insights into the physiology and pathology of ocular disease. This Core will augment our institution's commitment to devote major resources to the study of ocular diseases of its patients, especially diseases that still result in blindness despite current therapies, with the long-term goal of developing new therapies for these conditions.
拟议的核心设施旨在加强和提高新环境倡议支持的效率

项目成果

期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)

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Janey L Wiggs其他文献

Janey L Wiggs的其他文献

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{{ truncateString('Janey L Wiggs', 18)}}的其他基金

Defining early-onset glaucomagenetic etiologies
定义早发性青光眼病因
  • 批准号:
    10249270
  • 财政年份:
    2020
  • 资助金额:
    $ 16.21万
  • 项目类别:
Defining early-onset glaucomagenetic etiologies
定义早发性青光眼病因
  • 批准号:
    10448282
  • 财政年份:
    2020
  • 资助金额:
    $ 16.21万
  • 项目类别:
Defining early-onset glaucomagenetic etiologies
定义早发性青光眼病因
  • 批准号:
    10662296
  • 财政年份:
    2020
  • 资助金额:
    $ 16.21万
  • 项目类别:
Defining early-onset glaucomagenetic etiologies
定义早发性青光眼病因
  • 批准号:
    10034199
  • 财政年份:
    2020
  • 资助金额:
    $ 16.21万
  • 项目类别:
Genetic Risk Factors for Central Vision Loss in Glaucoma
青光眼中央视力丧失的遗传风险因素
  • 批准号:
    8622199
  • 财政年份:
    2013
  • 资助金额:
    $ 16.21万
  • 项目类别:
Genetic Risk Factors for Central Vision Loss in Glaucoma
青光眼中央视力丧失的遗传风险因素
  • 批准号:
    8510304
  • 财政年份:
    2013
  • 资助金额:
    $ 16.21万
  • 项目类别:
NEIGHBORHOOD Consortium for POAG Genetics
POAG 遗传学 NEIGHBORHOOD 联盟
  • 批准号:
    9148181
  • 财政年份:
    2012
  • 资助金额:
    $ 16.21万
  • 项目类别:
NEIGHBORHOOD Consortium for POAG Genetics
POAG 遗传学 NEIGHBORHOOD 联盟
  • 批准号:
    9173545
  • 财政年份:
    2012
  • 资助金额:
    $ 16.21万
  • 项目类别:
The NEIGHBORHOOD: POAG Heritable Overall Operational Database
NEIGHBORHOOD:POAG 可遗传整体运营数据库
  • 批准号:
    8265099
  • 财政年份:
    2012
  • 资助金额:
    $ 16.21万
  • 项目类别:
The NEIGHBORHOOD: POAG Heritable Overall Operational Database
NEIGHBORHOOD:POAG 可遗传整体运营数据库
  • 批准号:
    8511668
  • 财政年份:
    2012
  • 资助金额:
    $ 16.21万
  • 项目类别:

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