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中文摘要
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描述(由申请人提供) 环境诱变剂学会(EMS)是促进DNA修复和诱变基本机制研究的主要科学协会,并将这些知识应用于了解暴露于环境基因毒素对人类健康的影响。EMS科学家对DNA修复和突变的研究与对遗传和获得性基因改变的研究相结合,这些基因改变使个人容易患癌症、过早衰老和其他疾病。从根本上了解细胞、组织和整个生物体对遗传毒物的反应的机制和后果,对于制定关于环境健康危害的知情监管决策至关重要。多学科基础研究和应用研究的整合对这一进程至关重要。这种融合仍然是环境管理体系的中心重点,年度会议是传播信息和促进实现这一目标所必需的互动的关键。此外,这些会议为学生和博士后研究人员提供了一个重要的论坛,让他们在鼓励开放交流思想的环境中展示他们的研究成果,并与各自领域的领先科学家互动。第39届环境管理学会年会将于2008年10月18日至22日在波多黎各的里奥格兰德举行。它的主题是“基因与环境:从分子机制到风险”。该科学计划涵盖了EMS内的所有科学兴趣,由研讨会、研讨会、专题评论、全体讲座以及投稿的海报和平台会议组成。在EMS的整个历史中,EMS年会聚集了学术界、工业界和政府的科学家,他们对环境因素如何导致遗传毒性感兴趣。为会议提供资金支持对于实现这一使命是至关重要的。这项会议赠款申请的双重目标是为参加2008年EMS年会的学生和博士后研究员申请旅费奖励,以及为主要非成员演讲者的旅费提供部分资金。EMS相信,它的学生和博士后研究人员是该学会的未来,也是其科学家社区培养的科学努力的未来。旅行奖励有助于抵消否则可能使受训人员无法参加的财政负担。该应用程序还要求提供资金,以部分支付受邀的非成员发言者的旅费。EMS成员发言人均同意自费参会费用。然而,有必要帮助特邀非成员发言者支付旅费,因为他们为世界级会议提供了必要的思想交流。
英文摘要
DESCRIPTION (provided by applicant) The Environmental Mutagen Society (EMS) is the primary scientific society fostering research on the basic mechanisms of DNA repair and mutagenesis and application of this knowledge to understanding human health effects from exposure to environmental genotoxins. Studies of DNA repair and mutagenesis by EMS scientists are integrated with research on inherited and acquired genetic alterations that predispose individuals to cancer, premature aging, and other diseases. Fundamental understanding of the mechanisms and consequences of cellular, tissue, and whole organism responses to genotoxic agents is crucial to informed regulatory decision-making with respect to environmental health hazards. The integration of multi-disciplinary basic and applied research is essential to this process. Such integration remains the central focus of the EMS, and the annual meetings are key to the dissemination of information and fostering of interactions that are necessary to achieve it. In addition, the meetings provide an important forum for students and postdoctoral investigators to present their research and to interact with leading scientists in their field in a setting that encourages open exchange of ideas. The 39th Annual Meeting of the EMS will be held in Rio Grande, Puerto Rico from October 18 - 22, 2008. Its theme is "Genes and the Environment: From Molecular Mechanisms to Risk". The scientific program, which encompasses the full range of scientific interests within EMS, is comprised of symposia, workshops, topical reviews, plenary lectures, and contributed poster and platform sessions. Throughout its history, the EMS Annual Meetings have brought together academic, industrial and governmental scientists interested in how environmental factors lead to genotoxicity. Awarded funding support for the meeting is critically necessary in order to achieve this mission. The dual objectives of this conference grant application are to request funds for travel awards to students and postdoctoral fellows to attend the 2008 EMS Annual Meeting, and funds to partially support travel expenses for key non-member speakers. EMS believes that its students and postdoctoral investigators are the future of both the Society and the scientific endeavors fostered by its community of scientists. Travel awards assist in offsetting the financial burden that might otherwise prevent trainees from attending. The application also requests funds to partially defray travel costs for invited non-member speakers. EMS member speakers all agree to cover their own expenses for participation in the conference. However, it is necessary to assist with travel expenses for invited non-member speakers, who provide the cross- fertilization of ideas necessary for a world-class meeting.
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Novel Interactions of DNA Repair Processes in Replication Fork Maintenance
Novel Interactions of DNA Repair Processes in Replication Fork Maintenance
Novel Interactions of DNA Repair Processes in Replication Fork Maintenance
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