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中文摘要
翻译
DNA修复机器结构细胞生物学项目(SBDR)的行政核心(ADM)将协调项目的所有行政方面,并促进研究人员之间的互动。我们的目标是保持SBDR项目的一致性、重点和进展,以确保拟议研究的成功进行。具体来说,ADM核心将提供管理基础设施,确保里程碑的实现,并促进SBDR项目和核心之间以及更广泛的DNA修复和癌症研究社区之间的互动和有效沟通。行政核心的基础设施已经到位并有效运作,这是在可持续发展战略的九年历史中建立起来的。
英文摘要
The Administrative Core (ADM) of the Program Project in Structural Cell Biology of DNA Repair Machines (SBDR) will coordinate all administrative aspects of the Program and facilitate interaction among the Investigators. Our goal is to maintain the SBDR program coherence, focus, and progress to ensure the successful conduct of the proposed research. Specifically, the ADM Core will provide administrative infrastructure, ensure milestones are met, and promote interaction and efficient communication among SBDR Projects and Cores and with the wider DNA repair and cancer research communities. The infrastructure for the Administrative Core is already in place and operating efficiently, having been established during the nine-year history of SBDR. ADM Core goals will be accomplished through three specific aims: Aim 1. Provide management support to the SBDR Program. Aim 2. Facilitate and monitor SBDR progress and effective allocation of shared research Core efforts. Aim 3. Ensure effective communication between the NCI, investigators, and postdoctoral fellows. Management of the SBDR Program will be provided by an administrative structure that formally consists of Drs. Priscilla Cooper and John Tainer as Core Director and Deputy Director, respectively, together with the Program Communications Coordinator and an Executive Committee comprised of the Project Leaders, selected additional Sr. Investigators, and the EMB and SCB Core Directors. An External Advisory Board comprised of leading investigators in DNA repair, structural biology, and cancer biology will annually review the progress of the Program and make recommendations to the ADM Core Director and Deputy Director. The successful operation of the SBDR Program for 21 investigators at 15 institutions depends heavily on excellent communications and program management capabilities. The Administrative Core serves to provide a central point of contact for all operational matters with in SBDR. This includes providing budget management support, coordinating preparation of annual progress reports, monitoring progress toward overall SBDR goals, maintaining effective and equitable access to the shared resource Cores, and organizing regular teleconferences and web-based conferencing, postdoc webinars, and annual workshops for all investigators and SBDR fellows.
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Genomic Instability from Loss of XPG, a BRCA1/2 Partner: Role in Ovarian Cancer?
Novel Interactions of DNA Repair Processes in Replication Fork Maintenance
Novel Interactions of DNA Repair Processes in Replication Fork Maintenance
Novel Interactions of DNA Repair Processes in Replication Fork Maintenance
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