31st NATIONAL MEDICINAL CHEMISTRY SYMPOSIUM

描述（由申请人提供）：匹兹堡大学将主办第31届全国药物化学研讨会（2008年6月15日至19日），由美国化学会（ACS）药物化学部组织。PI，巴里金博士（药学院药学系），担任研讨会主席。这个一年两次的研讨会在一个论坛上展示了药物化学领域令人兴奋的新发展，该论坛促进了与会者之间的讨论，并确定了未来研究中要解决的最优先科学挑战。与会者来自美国和加拿大以及欧洲和亚洲。接受培训的年轻调查员是这一对话的重要组成部分。我们寻求R13资助旅行奖被授予竞争力的10名博士前和5名博士后学员选择在研讨会上做海报演示。 2008年研讨会包括8个口头会议和2个海报会议。口头会议，其中每个包括5个演示文稿，解决主题核酸靶向，癌症靶点，丙型肝炎，体外和体内药代动力学，生物标志物/PET，炎症/免疫学，虚拟库设计和筛选加上时间，以解决会议规划期间未考虑的最新主题。研讨会计划由来自行业（Mark Murkco博士，Vertex Pharmaceuticals，Boston，MA）和学术界（Peter Wipf博士，宾夕法尼亚州匹兹堡大学艺术与科学学院化学系）的代表共同主持，他们选择了口头会议主题，并将在相关会议上监测主题，以避免内容重叠并突出最新的发展。 海报会议是会议的一个重要组成部分，特别是对博士前和博士后学员来说，他们有一个论坛，向来自学术界、工业界和政府的杰出观众展示他们的研究。海报会议不与口头报告重叠，因此所有研讨会与会者都可以参加每个会议。海报摘要必须在2008年1月8日之前提交，并将由一个专家科学小组进行审查，以便在研讨会上发表，并考虑获得R13支持的旅行奖。NIH的资金将用于报销旅行奖获得者的注册费，校园住宿，颁奖宴会和机票。

DESCRIPTION (provided by applicant): The University of Pittsburgh will host the 31st National Medicinal Chemistry Symposium (June 15-19, 2008) organized by the Division of Medicinal Chemistry of the American Chemical Society (ACS). The PI, Dr. Barry Gold (Department of Pharmaceutical Sciences, School of Pharmacy), serves as the Symposium Chair. This biannual Symposium presents exciting and novel developments in the field of medicinal chemistry in a forum that fosters discussion among attendees and identifies scientific challenges of highest priority to be addressed in future research. Attendees come from throughout the US and Canada as well as Europe and Asia. Young investigators in training are an important part of this dialogue. We seek R13 funding for travel awards to be awarded competitively to 10 pre-doctoral and 5 post-doctoral trainees selected to make poster presentations at the Symposium. The 2008 Symposium includes 8 oral sessions and 2 poster sessions. The oral sessions, each of which includes 5 presentations, address topics in nucleic acids targeting, cancer targets, hepatitis C, in vitro and in vivo pharmacokinetics, biomarkers/PET, inflammation/immunology, and virtual library design and screening plus time to address late-breaking topics not contemplated during the conference planning period. The Symposium Program is co-chaired by representatives from industry (Dr. Mark Murkco, Vertex Pharmaceuticals, Boston, MA) and academia (Dr. Peter Wipf, Department of Chemistry, School of Arts & Sciences, University of Pittsburgh, PA) who selected the oral session topics and will monitor themes at related meetings to avoid overlap in content and highlight late-breaking developments. The poster sessions comprise a critical component of the meeting, especially for pre- and post-doctoral trainees, who are given a forum at which to present their research to a distinguished audience from academia, industry, and government. The poster sessions do not overlap with the oral presentations so all symposia attendees can participate in each session. Poster abstracts must be submitted by January 8, 2008 and will be reviewed by an expert scientific panel both for acceptance for presentation at the Symposium and for consideration for an R13-supported travel award. NIH funds will be used to reimburse travel award recipients for the registration fee, campus lodging, awards banquet, and airfare.