AOSSM Post-Joint Injury Osteoarthritis Conference

AOSSM 关节损伤后骨关节炎会议

基本信息

项目摘要

DESCRIPTION (provided by applicant): Osteoarthritis (OA) is the most common joint disease and is a leading cause of disability worldwide [1,2] . The physical impairment from OA of a single lower extremity joint is equivalent to that reported for major life-altering disorders such as end-stage kidney disease and heart failure. The causes of OA are not well understood. [3] However, joint trauma is a leading etiological factor [1,2,4] . Patients sustaining ligament and meniscal injuries of the knee have a ten-fold increased risk of OA when compared to those who did not have a joint injury [7,8] . Twelve years after an anterior cruciate ligament tear, 82% of female soccer players had pathological changes on knee radiographs and 75% had symptoms affecting their knee related quality of life at an average age of just 31 years old [9,10] . Concomitant meniscal injury is associated with an even higher prevalence of knee OA. ACL and meniscal injuries are the most common joint injuries treated by orthopaedic surgeons. The American Orthopaedic Society for Sports Medicine (AOSSM) is a national organization of orthopaedic surgeons dedicated to sports medicine and focuses on the treatment of injuries commonly sustained by active individuals. Formed in 1972 primarily as a forum for education and research, the AOSSM is now a world leader in sports medicine education, research, communication, and fellowship. A current AOSSM strategic priority is to evaluate methods to support and improve the quality of sports medicine research by identifying critical areas for study and by convening researchers with clinicians to exchange information and develop research priorities. The purpose of this conference is to convene leaders in the field to explore the strong association between joint injury and the development of osteoarthritis. Both clinical leaders and basic scientists will be brought together to determine the current and emerging areas of research, to develop a consensus on future directions in new areas of cooperative research, and to develop new collaborations and strategies for the translation of basic research into patient care. The AOSSM Post-joint Injury Osteoarthritis symposium will be December 11-14, 2008 in New Orleans, LA at a fully-accessible hotel and meeting center. Each session will be moderated by an AOSSM clinician-scientist, and a scientist with expertise in the session topic. The organizers and the faculty are a diverse group, both men and women, from the different parts of the US and abroad. Other participants will include 10 Young Investigators (YI), 14 at-large participants, 5 representatives from industry, and 5 representatives from the NIH. The YI Program will give up to 10 residents/scientists the opportunity to attend. YI applicants must be under 42 years of age or less than 8 years beyond training. The results of the symposium will be disseminated to the musculoskeletal community through publication in the American Journal of Sports Medicine an AOSSM monograph and will also be freely available to the public on the AOSSM website. People suffering injuries to their joints are at high risk of developing disabling wear and tear osteoarthritis in the prime of their lives. This symposium will bring doctors and scientists together to develop research plans to find new methods to prevent this from happening.
描述(由申请人提供):骨关节炎(Osteoarthritis, OA)是最常见的关节疾病,是全球致残的主要原因之一[1,2]。单个下肢关节骨性关节炎造成的身体损害相当于主要改变生活的疾病,如终末期肾病和心力衰竭。骨性关节炎的病因尚不清楚。然而,关节创伤是主要的病因[1,2,4]。与没有关节损伤的患者相比,膝关节韧带和半月板损伤的患者患OA的风险增加了10倍[7,8]。前十字韧带撕裂12年后,82%的女足球运动员在平均年龄仅31岁时膝关节x线片上出现病理改变,75%出现影响膝关节相关生活质量的症状[9,10]。伴随的半月板损伤与更高的膝关节OA患病率相关。前交叉韧带和半月板损伤是骨科医生治疗的最常见的关节损伤。美国运动医学矫形学会(AOSSM)是一个致力于运动医学的国家矫形外科医生组织,专注于运动个体通常遭受的伤害的治疗。AOSSM成立于1972年,最初是一个教育和研究论坛,现在是世界运动医学教育、研究、交流和奖学金的领导者。当前AOSSM的战略重点是通过确定研究的关键领域和召集研究人员与临床医生交流信息和制定研究重点来评估支持和提高运动医学研究质量的方法。本次会议的目的是召集该领域的领导者探讨关节损伤与骨关节炎发展之间的紧密联系。临床领导者和基础科学家将聚集在一起,确定当前和新兴的研究领域,就新的合作研究领域的未来方向达成共识,并制定新的合作和战略,将基础研究转化为患者护理。AOSSM关节损伤后骨关节炎研讨会将于2008年12月11日至14日在洛杉矶新奥尔良的一个无障碍酒店和会议中心举行。每次会议将由一名AOSSM临床科学家和一名在会议主题方面具有专业知识的科学家主持。组织者和教师是一个多元化的群体,有男有女,来自美国和国外的不同地区。其他参与者将包括10名青年研究者(YI), 14名普通参与者,5名行业代表和5名NIH代表。YI计划将提供最多10名居民/科学家参加的机会。YI申请人必须在42岁以下或培训后不超过8年。研讨会的结果将通过在《美国运动医学杂志》上发表的AOSSM专著向肌肉骨骼界传播,并将在AOSSM网站上免费向公众提供。关节受伤的人在壮年时患致残性磨损性骨关节炎的风险很高。这次研讨会将把医生和科学家聚集在一起,制定研究计划,寻找防止这种情况发生的新方法。

项目成果

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{{ truncateString('CONSTANCE R CHU', 18)}}的其他基金

BCCMA: Targeting Osteoarthritis Pain and Progression: Defining biologic and inflammatory markers associated with rapid progression
BCCMA:针对骨关节炎疼痛和进展:定义与快速进展相关的生物和炎症标志物
  • 批准号:
    10486497
  • 财政年份:
    2023
  • 资助金额:
    $ 2.5万
  • 项目类别:
Precision Assessment of Platelet Rich Plasma for Joint Preservation
富含血小板血浆对关节保护的精确评估
  • 批准号:
    10543976
  • 财政年份:
    2018
  • 资助金额:
    $ 2.5万
  • 项目类别:
Precision Assessment of Platelet Rich Plasma for Joint Preservation
富含血小板血浆对关节保护的精确评估
  • 批准号:
    10731741
  • 财政年份:
    2018
  • 资助金额:
    $ 2.5万
  • 项目类别:
AOSSM Post-joint Injury Conference II
AOSSM 关节损伤后会议 II
  • 批准号:
    8062988
  • 财政年份:
    2010
  • 资助金额:
    $ 2.5万
  • 项目类别:
Chondrogenesis In Situ
原位软骨形成
  • 批准号:
    8073319
  • 财政年份:
    2010
  • 资助金额:
    $ 2.5万
  • 项目类别:
Multicenter Cartilage Repair Preclinical Trial in Horses
马的多中心软骨修复临床前试验
  • 批准号:
    7943883
  • 财政年份:
    2009
  • 资助金额:
    $ 2.5万
  • 项目类别:
Multicenter Cartilage Repair Preclinical Trial in Horses
马的多中心软骨修复临床前试验
  • 批准号:
    7854800
  • 财政年份:
    2009
  • 资助金额:
    $ 2.5万
  • 项目类别:
Image Guided Debridement of Articular Cartilage
图像引导关节软骨清创术
  • 批准号:
    7667786
  • 财政年份:
    2008
  • 资助金额:
    $ 2.5万
  • 项目类别:
Chondrogenesis In Situ
原位软骨形成
  • 批准号:
    8098826
  • 财政年份:
    2007
  • 资助金额:
    $ 2.5万
  • 项目类别:
Chondrogenesis In Situ
原位软骨形成
  • 批准号:
    8799194
  • 财政年份:
    2007
  • 资助金额:
    $ 2.5万
  • 项目类别:

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激素治疗、绝经年龄、既往产次和 APOE 基因型会影响老年人的认知。
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