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A RANDOMIZED CONTROLLED TRIAL TO EVALUATE THE SAFETY OF LONG-TERM PEGYLATED A-A

A RANDOMIZED CONTROLLED TRIAL TO EVALUATE THE SAFETY OF LONG-TERM PEGYLATED A-A
评估长期聚乙二醇化 A-A 安全性的随机对照试验
批准号：
7716677
负责人：
KAREN L LINDSAY
金额：
$31.12万
依托单位：
UNIVERSITY OF SOUTHERN CALIFORNIA
依托单位国家：
美国
项目类别：
财政年份：
2008
资助国家：
美国
项目状态：
已结题
起止时间：
2008-04-20 至 2008-11-30
来源：
https://reporter.nih.gov/project-details/7716677
关键词：
RANDOMIZEDCONTROLLEDTRIALEVALUATESAFETY

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中文摘要
翻译
这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 该研究的主要目的是进行一项随机对照试验，以确定长期干扰素治疗是否可以合理地降低慢性丙型肝炎和晚期纤维化或肝硬化患者组织学进展为肝硬化，失代偿性肝病和/或肝细胞癌的风险，这些患者对既往干扰素治疗无效。
英文摘要
This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The primary objective of the study is to conduct a randomized, controlled trial to determine if long-term interferon therapy can reasonably reduce the risk of histologic progression to cirrhosis, decompensated liver disease and/or hepatocellular carcinoma in patients with chronic hepatitis C and advanced fibrosis or cirrhosis who failed to respond to previous interferon therapy.
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A RANDOMIZED CONTROLLED TRIAL TO EVALUATE THE SAFETY OF LONG-TERM PEGYLATED A-A
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