ANCILLARY STUDY TO THE HEPATITIS C ANTIVIRAL LONG-TERM TREATMENT AGAINST CIRR

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 建立一个慢性丙型肝炎患者队列，这些患者在接受聚乙二醇化干扰素和利巴韦林联合治疗后出现持续的病毒学应答(SVR)，并评估临床结果(静脉曲张出血、腹水、CTP评分和GT；7、肝移植、死亡)和肝细胞癌(肝细胞癌)的频率和与这些结果相关的因素。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. To establish a cohort of chronic hepatitits C patients with Ishak stage 3-6 fibrosis who experienced a sustained virologic response (SVR) after peginterferon and ribavarin combination therapy and assess the frequency of clinical outcomces (variceal bleeding, ascites, CTP scores> 7, liver transplants, death) and heptocellular carcinoma (HCC) and factors associated with these outcomes.