Structure-based design for neutralizing antibodies against SIV/HIV
Structure-based design for neutralizing antibodies against SIV/HIV
批准号:
7508914
负责人:
ELLIS L REINHERZ
金额:
$13.33万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2007
资助国家:
美国
项目状态:
已结题
起止时间:
2007-08-01 至 2008-01-31
关键词:
AdjuvantAffinityAntibodiesAntibody FormationAntigensBindingBinding SitesBiological AssayBostonCCR5 geneCD4 Positive T LymphocytesCaviaCell physiologyCellsChimeric ProteinsComplement 3dComplexCrystallizationDana-Farber Cancer InstituteDictyostelium discoideumElementsEscherichia coliFab ImmunoglobulinsFaceFluorescence PolarizationG-substrateGenerationsHIVHIV envelope proteinHIV-1Helper-Inducer T-LymphocyteImmunityImmunizationImmunologic Deficiency SyndromesImmunosuppressive AgentsIn VitroIndividualInstructionLinkMammalsMolecularNamesNatureNumbersPichiaPrincipal InvestigatorPrintingProcessProductionProtein FragmentProteinsResearch Project GrantsSIVSiteSolubilitySpecific qualifier valueStructureSurface Plasmon ResonanceSystemT-LymphocyteTestingVaccinationVaccine DesignVirus DiseasesX-Ray Crystallographybasedesignenv Gene Productsimmunogenicityin vivoinhibitor/antagonistneutralizing antibodyprogramsprotein protein interactionresponsesimian human immunodeficiency virus
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