Adherence in Adolescents with HIV: The Impact of Body Dissatisfaction

描述（由申请人提供）：鉴于青年艾滋病毒的流行率不断上升，加上这一人群的药物依从性较差。申请人希望通过检查身体形象、药物依从性和饮食失调之间的关系来探索对该人群产生负面影响的因素。具体而言，申请人感兴趣的是探索身体不满意是否是正在接受抗逆转录病毒药物治疗的青少年人群中药物依从性的显著差异，以及这种关系的性质是否受年龄和/或性别的调节。考虑到身体不满意和饮食失调之间的密切关系，作为第二个目的，申请人希望检查正在接受药物治疗的HIV青少年的身体不满意是否与饮食失调行为相关（例如，限制性节食、过度运动、补偿性行为），以及身体不满与饮食失调之间的关系是否受年龄和/或性别的调节。此外，申请方希望通过确定身体不满是否局限于可能受药物副作用影响的特定身体部位，进一步了解该人群中身体形象的性质。鉴于这项研究的结果可以提供有关身体形象如何影响药物依从性和饮食失调的有价值的信息，这些发现可能会导致未来在这一未充分研究领域的研究，也可以为心理健康和为青少年提供服务的医疗提供者提供指导艾滋病毒，因此，代表了NIH的使命进行改善健康的研究。 公共卫生相关性：有大量的研究已经研究了与青少年服用处方药相关的因素（例如，社会耻辱，财务和许多药丸）;然而，缺乏研究如何看待一个人对自己的身体或身体形象的感觉可能会影响这一人群。其他对患有慢性病的青少年进行的研究表明，身体形象不佳可能是导致治疗效果不佳的一个因素。此外，不良的身体形象一再被证明是饮食失调的预测，这有许多负面的健康结果。因此，这项研究将提供关于身体形象如何影响艾滋病毒感染青少年治疗的重要信息。这一人群的身体形象是严重不足的研究，这些信息将是有价值的未来研究和医疗设施，为这一人群提供治疗。

DESCRIPTION (provided by applicant): Given the rising prevalence of HIV in youth in addition to poor medication adherence in this population. The applicant desires to explore factors that are impacting this population negatively, by examining the relationship among body image, medication adherence, and disordered eating. Specifically, the applicant is interested in exploring if body dissatisfaction accounts for a significant amount of variance in medication adherence in a population of adolescents being treated with antiretroviral medications, and if the nature of this relation is moderated by age and/ or gender. Given the strong relation between body dissatisfaction and disordered eating, as a second aim, the applicant would like to examine if body dissatisfaction in adolescents with HIV who are being treated with medication is associated with disordered eating behavior (e.g., restrictive dieting, excessive exercise, compensatory behaviors) and if the relation between body dissatisfaction and disordered eating is moderated by age and/or gender. Additionally, the applicant wants to gain further understanding of the nature of body image within this population by determining if body dissatisfaction is localized to specific body parts that may be impacted by medication side effects. Given that the results of this study could provide valuable information on how body image may be impacting medication adherence and disordered eating, the findings could lead to future research in this understudied area and could also provide guidance for mental health and medical providers serving adolescents with HIV, and thus, is representative of NIH's mission to conduct research that improves health. PUBLIC HEALTH RELEVANCE: There is a great deal of research that has studied factors that are associated with adolescents taking their prescribed medications (e.g., social stigma, finances, and numerous pills); however, there is a dearth of studies looking at how one's feelings about their body or body image may be impacting this population. Other studies that have worked with adolescents with chronic illnesses have suggested that poor body image may be a factor that leads to poor treatment outcomes. Additionally, poor body image has been shown repeatedly to be predictive of eating disorders, which have many negative health outcomes. Therefore, this study will supply important information on how body image may be impacting treatment in adolescents with HIV. Body image in this population is severely understudied and this information will be valuable to future research and medical facilities that provide treatment to this population.