Manifestation & Effect of Patient-Ventilator Dysynchrony

表现

• 批准号: 7393336
• 负责人: Karen G. Mellott
• 金额: $ 3.33万
• 依托单位: VIRGINIA COMMONWEALTH UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-04-15 至 2009-04-14
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7393336
• 关键词: Agitation; Anxiety; Asses; Behavior; Behavioral; Cardiovascular system; Caring; Client; Clinical; Clinical Nurse Specialists; Critical Illness; Data; Dependence; Detection; Diagnostic tests; Economic Burden; Ensure; Environmental air flow; Evaluation; Fatigue; Fellowship; Gases; Gross National Product; Healthcare; Heart Rate; Hospitalization; Hour; Hypercapnia; Injury; Intensive Care Units; Lead; Measures; Mechanical ventilation; Methods; Nurses; Patient observation; Patients; Physicians; Physiological; Rate; Reporting; Research; Research Personnel; Respiratory Muscles; Rest; Risk; Sedation procedure; Sleep; Technology; Tube; United States; Ventilator; Work; Workload; actigraphy; base; biobehavior; cost; design; endotracheal; improved; pressure; prevent; respiratory

Patient-ventilator synchrony is critical in achieving optimal oxygenation and ventilation. However,ventilator synchrony is difficult to quantify. Nurses often asses patient-ventilator dysnchrony (PVD) using a non- empirical approach, and clinical manifestations of dysychrony are not standardized. Identifying valid biobehavioral measures of this phenomenon will assist clinicians to reduce the complications of mechanical ventilation. Thus, the specific aims of this fellowship are to: 1) Identify biobehavioral markers (physiologic stability, agitation and patient behavior) of patient-ventilator dysnchrony and 2) Examine the effect of patient ventilator dysynchrony on the use of sedation. Patient ventilator dysynchrony will be identified using changes in airway pressure waveforms that will be obtained continuously over a 24-hour period. The bio- behavioral markers of patient-ventilator dysynchrony to be evaluated in this study will include physiologic instability (heart rate, SaO2, respiratory rate), agitation (actigraphy) and direct observation of patient behav- iors as well as amount of sedation use. Describing PVD will assist clinicians in early and accurate detection of dysynchrony, which may lead to reduction in risks associated with mechanical ventilation and sedation.

患者 - 温易语剂同步对于实现最佳氧合和通风至关重要。但是，呼吸机 同步很难量化。护士经常使用非 - 经验方法和染色体的临床表现未标准化。确定有效 这种现象的生物行为测量方法将有助于临床医生减少机械并发症 通风。因此，该奖学金的具体目的是：1）识别生物行为标记（生理标记 稳定性，躁动和患者行为）患者 - 视毒剂异常和2）检查患者的效果 呼吸机对使用镇静作用。使用患者呼吸机dysynchrony使用 气道压力波形的变化将在24小时内连续获得。生物 - 在这项研究中评估的患者 - 视频剂量疾病的行为标记将包括生理 不稳定性（心率，SAO2，呼吸速度），躁动（行动语义）和直接观察患者行为 IORS以及镇静的数量。描述PVD将帮助临床医生尽早检测 dysnchrony的作用，这可能导致与机械通气和镇静有关的风险降低。