Muscle Stem Cell-based therapies for Cardiomyopathy

基于肌肉干细胞的心肌病疗法

• 批准号: 7509214
• 负责人: JOHNNY HUARD
• 金额: $ 9.4万
• 依托单位: UNIVERSITY OF PITTSBURGH AT PITTSBURGH
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-06-01 至 2009-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7509214
• 关键词: Adenovirus Vector; Adult; Adverse effects; Affect; Angiogenic Factor; Animals; Appendix; Area; Autologous; Behavior; Biological; Biological Assay; Biological Process; Biology; Blood; Blood Vessels; Bone Marrow; Bone Regeneration; Cardiac; Cardiac Myocytes; Cardiomyopathies; Cardiomyoplasty; Cardiovascular Diseases; Cardiovascular system; Cell Differentiation process; Cell Proliferation; Cell Survival; Cell Therapy; Cell Transplantation; Cells; Characteristics; Cicatrix; Collaborations; Condition; Congestive Heart Failure; Coupling; DNA; Data; Dermal; Development; Disease; Duchenne muscular dystrophy; Dystrophin; Embryo; Endothelial Cells; Engineered Gene; Engraftment; Ensure; Environment; Experimental Animal Model; Family suidae; Fibroblasts; Fibrosis; Fostering; Future; Genes; Genetic; Goals; Green Fluorescent Proteins; Harvest; Healed; Heart; Heart Atrium; Heart Diseases; Hematopoietic stem cells; Human; Immune; Implant; In Vitro; Injection of therapeutic agent; Injury; Karyotype; Kidney; LacZ Genes; Letters; Liver; Long-Term Effects; Luciferases; Lung; Mediating; Modeling; Multipotent Stem Cells; Mus; Muscle; Muscle Cells; Muscle Development; Muscle Fibers; Muscle satellite cell; Muscular Dystrophies; Myoblasts; Myocardial; Myocardium; Myofibroblast; Myopathy; Natural regeneration; Neonatal; Numbers; PTPRC gene; Patients; Performance; Phenotype; Play; Population; Procedures; Process; Production; Proliferating; Proteoglycan; Rate; Recovery; Regenerative Medicine; Relative (related person); Reporter Genes; Reporting; Research; Research Personnel; Retroviral Vector; Retroviridae; Rodent; Role; Route; Serum; Site; Skeletal Muscle; Skeletal Myoblasts; Skeletal system; Smooth Muscle Myocytes; Sorting - Cell Movement; Source; Staging; Stem cell transplant; Stem cells; Structure; Survival Rate; Switch Genes; System; Techniques; Technology; Therapeutic; Time; Tissue Engineering; Tissues; Transgenic Mice; Transplantation; Troponin I; Vascular Endothelial Growth Factors; angiogenesis; base; blood pump; cell dedifferentiation; cell type; decorin; design; dosage; embryonic stem cell; fetal; gene therapy; healing; hypertensive heart disease; implantation; improved; in vivo; inhibitor/antagonist; injured; loss of function; mdx mouse; muscle regeneration; muscle transplantation; novel; precursor cell; prevent; promoter; receptor; relating to nervous system; repaired; research study; response to injury; satellite cell; self-renewal; stem cell therapy; success; therapeutic gene; tumor; vector