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Prescription Drug Abuse Among Club Drug Users

俱乐部吸毒者中的处方药滥用情况

基本信息

批准号：
7480207
负责人：
JAMES A INCIARDI
金额：
$ 57.54万
依托单位：
UNIVERSITY OF DELAWARE
依托单位国家：
美国
项目类别：
财政年份：
2005
资助国家：
美国
起止时间：
2005-08-01 至 2010-07-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/7480207
关键词：
Adolescent Advocate African American Age Alcohols Alprazolam American Americas Amphetamines Anesthetics Area Arts Barbiturates British Chronic Clinical Medicine Cocaine Coercion Communities Daily Dancing Darvon Data Data Analyses Delaware Dental Calculus Destinations Dextroamphetamine Diazepam Disease Dormutil Drug Addiction Drug Combinations Drug Interactions Drug Prescriptions Drug abuse Drug usage Drug user England Epidemiology Ethnic Origin Fathers Female Florida Focus Groups Frequencies Future Gender General Population Goals Growth HIV Infections Hand Health Health Services Hispanics Household Hydrocodone Hydromorphone Impairment Institutes International Internet Intervention Investigation Ipecac Ketamine Latin America Legal Licorice Literature Medical Mental Health Mentors Meperidine Methamphetamine Methaqualone Methylphenidate Monitor National Institute of Drug Abuse Nature New York Non-Prescription Drugs Numbers Opioid Opium Overdose Oxycodone Participant Patients Pattern Pentazocine Percocet Pharmaceutical Preparations Pharmacologic Substance Physical activity Physicians Policies Population Powder dose form Preparation Prevalence Prevention Prevention program Principal Investigator Process Property Propoxyphene Publishing Race Recording of previous events Recruitment Activity Research Research Personnel Respondent Risk Risk-Taking Rohypnol Rural Sales Sampling Sampling Studies Sex Behavior Students Study Section Surveys Target Populations Techniques Theft Time United States United States Food and Drug Administration Universities Viagra Vicodin Vulnerable Populations Western Europe Wine Work Xanax barbituric acid salt club drug club drug abuse college coral drug abuser ecstasy experience innovation life history male member percodan population survey potassium nitrate preference prescription document prescription drug abuse prescription procedure programs promoter research study restoration sedative sex social trend young adult

项目摘要

DESCRIPTION (provided by applicant): The non-medical use of Pharmaceuticals has been a long-standing problem in the United States, and since the 1970s the use of "club drugs" has been a problem among adolescents and young adults. A recent trend has been the incursion of prescription drugs into the club culture, with the concomitant health consequences associated with their abuse. Because of their young age and their tendency to mix numerous drugs during any given drug binge, club drug users tend to be a highly vulnerable population. Within this context, the specific aims of this application are to; 1) recruit a sample of 750 out-of-treatment prescription and club drugs abusers ages 18-39 and at baseline assess their life histories of alcohol and drug abuse onset and progression, and extent of current alcohol and prescription, club and other drug use; 2) at 6, 12 and 18 months, assess changes in onset, progression, and extent of respondents' alcohol and prescription, club and other drug use; 3) at baseline, 6, 12 months and 18 months, assess the mechanisms of access to prescription drugs among the sampled drug users; 4) at baseline, 6, 12 and 18 months, investigate the impact of quantity, frequency, types and duration of prescription and club drug abuse on the nature and extent of health and social consequences within this population, including: sexual risk-taking and coercion; drug interactions and overdose; chronic drug use; impairment of daily activities; physical problems; mental health problems; and legal problems; and 5) examine the impact of gender and other potential correlates (sexual identity, sexual history, current sexual behaviors, drug history, and current drug use) on onset, progression, and extent of prescription, club and other drug abuse and the nature and extent of health and social consequences. The study sample will reflect the race/ethnic distribution of the Miami population: 30 percent white/Anglo, 50 percent Hispanic, and 20 percent African-American, with a gender distribution of 50 percent female and 50 percent male. A variety of statistical techniques will be used to describe the population, the epidemiology of prescription and other drug use in the club culture, and the nature and prevalence of related consequences. The short-term objectives are to describe the changing nature of prescription drug abuse/club drug use and their consequences in the Miami club culture. A broader long-term goal is to better understand current patterns of the abuse of prescription drugs and their incursion into the club culture, in order that strategies can be developed for reducing the abuse and diversion of these drugs in Miami and other communities. Such strategies and policies may ultimately reduce the abuse and diversion of prescription drugs, as well as make them more readily available to the patients for whom they are intended.

说明（由申请人提供）：药品的非医疗使用在美国是一个长期存在的问题，自1970年代以来，使用“俱乐部毒品”一直是青少年和青年中的一个问题。最近的一个趋势是，处方药物侵入俱乐部文化，滥用处方药物会带来健康后果。由于他们年轻，而且在任何一次吸毒狂欢中都有混合多种毒品的倾向，俱乐部吸毒者往往是一个非常脆弱的群体。在此上下文中，此应用程序的具体目标是：1)招募750名年龄在18-39岁的治疗外处方药物和俱乐部药物滥用者，并在基线时评估他们的酒精和药物滥用的开始和进展的生活史，以及目前酒精和处方药物、俱乐部和其他药物使用的程度；2)在6、12和18个月时，评估调查对象酒精和处方、俱乐部和其他药物使用的开始、进展和程度的变化；3)在基线、6个月、12个月和18个月，评估抽样吸毒者获得处方药的机制；4)在基线、6个月、12个月和18个月，调查处方药物和俱乐部药物滥用的数量、频率、类型和持续时间对这一人群中健康和社会后果的性质和程度的影响，包括：性冒险和性胁迫；药物相互作用和过量；长期吸毒；日常活动障碍；物理问题;精神健康问题；法律问题；5)检查性别和其他潜在相关因素（性身份、性史、当前性行为、药物史和当前药物使用）对处方、俱乐部和其他药物滥用的发作、进展和程度以及健康和社会后果的性质和程度的影响。研究样本将反映迈阿密人口的种族/民族分布：30%的白人/盎格鲁人，50%的西班牙裔，20%的非裔美国人，性别分布为50%的女性和50%的男性。将使用各种统计技术来描述人口，俱乐部文化中处方和其他药物使用的流行病学，以及相关后果的性质和流行程度。短期目标是描述处方药物滥用/俱乐部药物使用的变化性质及其在迈阿密俱乐部文化中的后果。一个更广泛的长期目标是更好地了解目前滥用处方药的模式及其对俱乐部文化的侵入，以便制定策略，减少迈阿密和其他社区滥用和转移这些药物。这种战略和政策可能最终减少处方药的滥用和转移，并使它们更容易为它们的目标患者所获得。