Bilateral cochlear implants: improving performance

双侧人工耳蜗：提高性能

• 批准号: 7380027
• 负责人: Donald Keith Eddington
• 金额: $ 31.92万
• 依托单位: MASSACHUSETTS EYE AND EAR INFIRMARY
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-04-04 至 2010-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7380027
• 关键词: Acoustic Nerve; Acoustics; Acute; Address; Algorithms; Area; Auditory system; Bilateral; Characteristics; Class; Clinical; Cochlear Implants; Cochlear implant procedure; Code; Complex; Condition; Cues; Depth; Ear; Electric Stimulation; Electrodes; Environment; Felis catus; Frequencies; Goals; Hearing; Image; Implant; Individual; Inferior Colliculus; Just-Noticeable Differences; Lead; Learning; Left; Localized; Location; Masks; Measurement; Measures; Methods; Motivation; Music; Nerve Fibers; Noise; Numbers; Pattern; Performance; Phase; Physiologic pulse; Physiological; Principal Investigator; Process; Psychophysics; Psychophysiology; Pulse Rates; Pulse taking; Rate; Research; Research Personnel; Scheme; Side; Signal Transduction; Source; Source Code; Speech; Speech Intelligibility; Standards of Weights and Measures; Stimulus; Structure; System; Testing; Thinking; Time; Today; Training; Travel; Weight; Work; attenuation; base; binaural hearing; computerized data processing; design; desire; hearing impairment; improved; interest; relating to nervous system; research study; response; sound; speech processing

DESCRIPTION (provided by applicant): Normal hearing is binaural and provides significant advantages over monaural listening. Listeners with two ears are able to more accurately localize sound sources and more accurately understand a talker in the presence of spatially-separated, competing sound-sources. These advantages are a primary motivation for bilateral cochlear implantation. In this application, experts in cochlear implants and binaural hearing join in an effort to better understand the factors associated with today's bilateral sound-processing strategies that limit performance and to design, implement and test new sound-processing strategies that minimize those limitations. Five bilaterally-implanted subjects will be studied in depth using psychophysical studies to characterize their basic bilateral sensitivity to interaural time difference (ITD) and interaural level difference (ILD) using single and multiple interaural-electrode pairs. These sensitivities will be compared to those of three new methods of bilateral stimulation. To the extent these new methods improve the interaural sensitivity as measured at the level of interaural-electrode pairs, we propose to incorporate them in speechprocessing strategies to determine whether they improve functional performance in acute testing. Because today's sound-processing strategies limit a subject's access to the interaural sensitivity available at the individual electrodes, we also propose to implement and acutely evaluate two speech-processing strategies designed to overcome these limitations. Those speech-processing strategies that show promise in functional testing will be implemented for longitudinal testing to assess asymptotic performance and learning.

描述（由申请人提供）：正常听力是双耳听力，与单耳听力相比具有显著优势。具有两只耳朵的听众能够更准确地定位声源，并且在存在空间分离的竞争声源的情况下更准确地理解说话者。这些优点是双侧人工耳蜗植入的主要动机。在这个应用程序中，人工耳蜗植入和双耳听力专家加入努力更好地了解与当今限制性能的双边声音处理策略相关的因素，并设计，实施和测试新的声音处理策略，最大限度地减少这些限制。将使用心理物理学研究对5名双侧植入受试者进行深入研究，以使用单个和多个耳间电极对表征其对耳间时间差（ITD）和耳间电平差（ILD）的基本双侧敏感性。这些敏感性将被比较的三种新的方法的双边刺激。在一定程度上，这些新方法提高了耳间电极对水平上测量的耳间灵敏度，我们建议将它们纳入语音处理策略，以确定它们是否改善了急性测试中的功能表现。由于今天的声音处理策略限制了受试者获得在个别电极可用的耳间灵敏度，我们还建议实施和尖锐地评估两个语音处理策略，旨在克服这些限制。那些在功能测试中表现出希望的语音处理策略将用于纵向测试，以评估渐进性能和学习。