A high sensitivity broad spectrum optical early warning system for chemical toxic agents in water

水中化学毒剂高灵敏度广谱光学预警系统

• 批准号: EP/E028624/1
• 负责人: Asim Ray
• 金额: $ 31.58万
• 依托单位: Queen Mary University of London
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2007
• 资助国家: 英国
• 起止时间: 2007 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=EP%2FE028624%2F1
• 关键词: sensitivity; broad; spectrum; optical; early

The collaborative project between Queen Mary, University of London andUniversity of East Anglia aims to design and engineer a low cost, portable,broad spectrum and highly sensitive integrated optical biosensor to be employedin rapid response warning systems for threats to water security. The solutionwill be based upon a multidisciplinary approach combining expertise in thesynthesis of novel tailor-made macrocyclic compounds (reporter materials),formulation of lipid bilayer membranes within a robust self-assembled organicfilm, high sensitive optical registration of surface/analyte interaction andall optical sensor interrogation methods. Fundamental investigations intochemical and engineering sciences will be targeted to meet the end users'specifications and the original scientific and engineering knowledge in thesensor technology will form the basis of a further technology transferprogramme into developing a marketable product by industrial collaborators. Itis important that any developed sensor is shown to be robust and fit forpurpose and instant feedback is essential for security alert. Minimalmaintenance requirements are to be achieved for commercially viable replacementof current practices. The detection limit should also be three orders ofmagnitude better than the ppm range capability of existing technologies.A common case for support is being submitted by QMUL and UEA.

玛丽女王大学、伦敦大学和东安格利亚大学之间的合作项目旨在设计和制造一种低成本、便携式、宽光谱和高灵敏度的集成光学生物传感器，用于对水安全威胁的快速反应预警系统。该解决方案将基于多学科方法，结合了新型定制大环化合物（报告材料）合成的专业知识，在稳健的自组装有机膜内配制脂质双层膜，表面/分析物相互作用的高灵敏度光学配准以及所有光学传感器询问方法。将针对化学和工程科学进行基础研究，以满足最终用户的规格要求，传感器技术中的原始科学和工程知识将构成进一步技术转让计划的基础，由工业合作者开发可销售的产品。重要的是，任何开发的传感器被证明是强大的，适合的目的和即时反馈是必不可少的安全警报。最低限度的维护要求是为了实现商业上可行的现行做法。检测极限也应该比现有技术的ppm范围能力好三个数量级。QMUL和UEA正在提交一个共同的支持案例。