Medical Genetics Training Grant

医学遗传学培训补助金

• 批准号: 7478164
• 负责人: Allen Everett Bale
• 金额: $ 15.1万
• 依托单位: YALE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-07-01 至 2010-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7478164
• 关键词: Grant; Medical Genetics; Training

DESCRIPTION (provided by applicant): This proposal seeks funding for continuation of a post doctoral training program in medical genetics designed to prepare individuals holding M.D., M.D./Ph.D., or Ph.D. degrees for independent research careers. During the past decade medical genetics has become integrated into the broad field of medicine. As a result of changes in this field, the Department of Genetics at Yale is receiving applications from medical specialists with previous clinical training in a variety of areas who are now seeking research training in genetics as well as more traditional candidates seeking both research and clinical training required for ABMG eligibility. Support is requested for a total of 4 stipends--2 for first-year fellows and 2 for second-year fellows. Typically, the program will fund two medical specialists per year who have completed most of their clinical training and wish to have a 2-year period of concentrated research in human genetics. Candidates seeking board eligibility in clinical genetics as well as research training will be supported from other sources during the bulk of clinical training. Most trainees will seek independent support for additional post doctoral training to make them more competitive for academic positions. In addition to M.D. candidates, a large number of applicants are recent graduates of Ph.D. programs seeking training in human genetics. It is anticipated that the program will accept a limited number of highly qualified Ph.D. applicants with a demonstrated commitment to human genetics research. The heart of this program will be participation in a research project under the direction of a primary preceptor and a committee made up of the director and other training faculty. Research areas supported by the training faculty include behavioral genetics, biochemical genetics, cancer genetics, cardiovascular genetics, cytogenetics, developmental genetics in humans and model organisms, genomics, immunogenetics, and population genetics. In addition a course in scientific integrity/medical ethics will be required and other course work will be tailored to the individual.

描述(由申请人提供)：本提案寻求为医学遗传学博士后培训计划的继续提供资金，该计划旨在为拥有医学博士、医学博士或博士学位的个人为独立研究职业做准备。在过去的十年里，医学遗传学已经融入了广泛的医学领域。由于这一领域的变化，耶鲁大学遗传学系正在接受来自多个领域曾接受过临床培训的医学专家的申请，他们现在正在寻求遗传学方面的研究培训，以及寻求ABMG资格所需的研究和临床培训的更传统的候选人。请拨共4笔津贴--第一年研究员两笔，第二年研究员两笔。通常情况下，该计划每年将资助两名医学专家，他们已经完成了大部分临床培训，并希望有两年的时间集中研究人类遗传学。在大部分临床培训期间，寻求临床遗传学和研究培训董事会资格的候选人将得到其他来源的支持。大多数学员将为额外的博士后培训寻求独立支持，以使他们在学术职位上更具竞争力。除了医学博士候选人，还有大量的申请者是新近毕业的博士研究生，他们正在寻求人类遗传学方面的培训。预计该计划将接受数量有限的高度合格的博士申请者，并证明他们致力于人类遗传学研究。该计划的核心将是在一名首席教师和一个由主任和其他培训人员组成的委员会的指导下参与一个研究项目。培训人员支持的研究领域包括行为遗传学、生化遗传学、癌症遗传学、心血管遗传学、细胞遗传学、人类和模式生物的发育遗传学、基因组学、免疫遗传学和群体遗传学。此外，还将要求开设一门关于科学诚信/医学伦理的课程，并为个人量身定做其他课程。

项目成果

Genomic characterization of prenatally detected chromosomal structural abnormalities using oligonucleotide array comparative genomic hybridization.

• DOI: 10.1002/ajmg.a.34043
• 发表时间: 2011-07
• 期刊: AMERICAN JOURNAL OF MEDICAL GENETICS PART A
• 影响因子: 2
• 作者: Li, Peining;Pomianowski, Pawel;DiMaio, Miriam S.;Florio, Joanne R.;Rossi, Michael R.;Xiang, Bixia;Xu, Fang;Yang, Hui;Geng, Qian;Xie, Jiansheng;Mahoney, Maurice J.
• 通讯作者: Mahoney, Maurice J.

A multiplex assay for the detection and mapping of complex glycerol kinase deficiency.

用于检测和绘制复杂甘油激酶缺陷的多重测定。

• DOI: 10.1373/clinchem.2006.072397
• 发表时间: 2006
• 期刊: Clinical chemistry
• 影响因子: 9.3
• 作者: Klein,RogerD;Thorland,ErikC;Gonzales,PatrickR;Beck,PatriciaA;Dykas,DanielJ;McGrath,JamesM;Bale,AllenE
• 通讯作者: Bale,AllenE

Clinical and genomic characterization of distal duplications and deletions of chromosome 4q: study of two cases and review of the literature.

• DOI: 10.1002/ajmg.a.33088
• 发表时间: 2009-12
• 期刊: AMERICAN JOURNAL OF MEDICAL GENETICS PART A
• 影响因子: 2
• 作者: Rossi, Michael R.;DiMaio, Miriam S.;Xiang, Bixia;Lu, Kangmo;Kaymakcalan, Hande;Seashore, Margretta;Mahoney, Maurice J.;Li, Peining
• 通讯作者: Li, Peining