Human embryo's secret weapon for implantation

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Embryo implantation is a critical step in establishing pregnancy, requiring stable attachment of an embryo to the uterus. For this to occur, the embryo must be implantation competent and the uterus must be receptive. However, to date, little is known about the interactions between the two that determine a successful implantation in the human. This project will investigate a novel embryo-derived enzyme that drives human implantation. These studies are important to improve infertility treatment.