R01D: An Interdisciplinary Perspective: A Social Science Examination of Oncoferti

R01D：跨学科视角：Oncoferti 的社会科学检验

• 批准号: 7502590
• 负责人: LINDA Leah EMANUEL
• 金额: $ 36.4万
• 依托单位: NORTHWESTERN UNIVERSITY AT CHICAGO
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-09-30 至 2012-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7502590
• 关键词: Adult; Attention; Biological Preservation; Cancer Patient; Child; Childhood; Clinical Trials; Costs and Benefits; Counseling; Cryopreservation; Decision Making; Depth; Economics; Ethnic Origin; Family; Family Physicians; Family member; Fertility; Focus Groups; Gender; Health Personnel; Healthcare; Infertility; Interview; Leadership; Legal; Life; Life Experience; Malignant Neoplasms; Medical; Modeling; Ovarian; Parents; Patients; Physicians; Play; Race; Religion and Spirituality; Reproductive Technology; Research; Role; Scholarship; Science; Social Characteristics; Social Sciences; Socioeconomic Status; Surveys; Technology; Time; Triad Acrylic Resin; Woman; bench to bedside; cancer diagnosis; ethical legal social implication; experience; malignant breast neoplasm; racial and ethnic; social; socioeconomics; survivorship; young adult

The aim of R01D is to advance scholarship at the interface of social and biomedical sciences that will promote and extend our ability to move emerging oncofertility technology from the bench to the bedside. Specifically, to comprehensively examine cancer patients' concerns regarding fertility and how patients, along with their families and physicians, make fertility-related healthcare decisions and to understand the social, legal, and ethical factors that surround those decisions at the time of cancer diagnosis. The proposed research agenda consists of five empirical projects and promotes a triad-model of healthcare decisionmaking whereby the roles of patients, family members (including parents and partners), and healthcare providers will be examined. Moreover, the proposed research agenda utilizes a triangulated methodological approach whereby qualitative and quantitative projects will explore the lived experience of infertility and cancer and will include survey instruments, in-depth interviews, and focus groups; and several projects will integrate mixed methodological approaches within their respective research plan. Project #1, under the direction of Dr. Linda Emanuel, Dr. Laurie Zoloth, and Prof. Dorothy Roberts, will look at the ethical and legal issues surrounding the use of reproductive technologies for cancer patients, with a special emphasis on the implications for pediatric patients and their families. Project #2, under the leadership of Dr. David Dranove, Dr. Andrew Sfekas, and Dr. Charles Bennett, is an economics analysis of how young adult women with cancer weigh the costs and benefits of possible infertility and fertility preservation treatments. Project #3, under the direction of Dr. Kathleen Galvin, Dr. Paul Arnston, and Dr. Maria Chapman, will explore how families facing a child's cancer diagnosis decide whether or not to participate in the ovarian cryopreservation clinical trial and the role that others, such as healthcare practitioners and religious counsel, play in this decision. The aim of this research is to understand how families facing a child's medical crisis make healthcare decisions and to develop a shared decision-making model aimed at informed choice. Project #4, under the direction of Dr. Karrie Snyder, will explore how adult women with breast cancer share their concerns regarding infertility with their physician, how they arrive at treatment decisions, and the impact of possible infertility on their lives and relationships after cancer, with special attention being paid to issues of racial/ethnic and socioeconomic diversity in patient's concerns and survivorship experiences. Project #5, under the direction of Prof. Matthew J. Loscalzo, will be a large-scale survey of cancer patients' concerns and treatment decisions and a comparison of these by key social characteristics including gender, race/ethnicity, socioeconomic status/and family status.

R 01 D的目的是在社会和生物医学科学的接口推进奖学金，将 促进和扩展我们将新兴的肿瘤生育技术从实验室转移到床边的能力。 具体来说，为了全面研究癌症患者对生育能力的担忧， 沿着他们的家人和医生，做出与生育相关的医疗保健决定，并了解 社会的、法律的和伦理的因素，这些因素在癌症诊断时围绕着这些决定。拟议 研究议程由五个实证项目组成，并促进了医疗决策的三元模型 患者、家庭成员（包括父母和伴侣）和医疗保健 供应商将接受检查。此外，拟议的研究议程采用了三角方法， 定性和定量项目将探索不孕症的生活经验， 癌症，并将包括调查工具，深入访谈，和焦点小组;和几个项目将 将混合方法纳入各自的研究计划。项目#1，根据 琳达伊曼纽尔博士，劳里Zoloth博士和教授多萝西罗伯茨的方向，将着眼于道德和法律的 围绕癌症患者使用生殖技术的问题，特别强调 对儿科患者及其家属的影响。项目2，在大卫Dranove博士的领导下， 博士安德鲁·斯菲卡斯和查尔斯班尼特博士，是一个经济学分析， 癌症权衡可能的不孕和生育保留治疗的成本和收益。项目#3， 在凯瑟琳·高尔文博士、保罗·阿恩斯顿博士和玛丽亚·查普曼博士的指导下， 面临孩子癌症诊断的家庭决定是否参与卵巢冷冻保存 临床试验和其他人的作用，如医疗从业人员和宗教顾问，在这方面发挥作用， 决定这项研究的目的是了解面临儿童医疗危机的家庭如何 卫生保健决策，并制定一个共同的决策模式，旨在知情选择。项目4， 在Karrie Snyder博士的指导下，将探索患有乳腺癌的成年女性如何分享她们的 关注不孕不育与他们的医生，他们如何达成治疗决定，以及影响 可能的不孕症对他们的生活和癌症后的关系，特别注意的问题， 种族/民族和社会经济多样性的患者的关注和生存经验。项目5， 在Matthew J. Loscalzo教授的指导下，将对癌症患者的担忧进行大规模调查 和治疗决定，并通过包括性别在内的关键社会特征进行比较， 种族/民族、社会经济地位/和家庭状况。