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R01D: An Interdisciplinary Perspective: A Social Science Examination of Oncoferti

R01D：跨学科视角：Oncoferti 的社会科学检验

基本信息

批准号：
8142926
负责人：
LINDA Leah EMANUEL
金额：
$ 35.72万
依托单位：
NORTHWESTERN UNIVERSITY AT CHICAGO
依托单位国家：
美国
项目类别：
财政年份：
2007
资助国家：
美国
起止时间：
2007-09-30 至 2012-12-30
项目状态：
已结题

项目摘要

The aim of R01D is to advance scholarship at the interface of social and biomedical sciences that will promote and extend our ability to move emerging oncofertility technology from the bench to the bedside. Specifically, to comprehensively examine cancer patients' concerns regarding fertility and how patients, along with their families and physicians, make fertility-related healthcare decisions and to understand the social, legal, and ethical factors that surround those decisions at the time of cancer diagnosis. The proposed research agenda consists of five empirical projects and promotes a triad-model of healthcare decisionmaking whereby the roles of patients, family members (including parents and partners), and healthcare providers will be examined. Moreover, the proposed research agenda utilizes a triangulated methodological approach whereby qualitative and quantitative projects will explore the lived experience of infertility and cancer and will include survey instruments, in-depth interviews, and focus groups; and several projects will integrate mixed methodological approaches within their respective research plan. Project #1, under the direction of Dr. Linda Emanuel, Dr. Laurie Zoloth, and Prof. Dorothy Roberts, will look at the ethical and legal issues surrounding the use of reproductive technologies for cancer patients, with a special emphasis on the implications for pediatric patients and their families. Project #2, under the leadership of Dr. David Dranove, Dr. Andrew Sfekas, and Dr. Charles Bennett, is an economics analysis of how young adult women with cancer weigh the costs and benefits of possible infertility and fertility preservation treatments. Project #3, under the direction of Dr. Kathleen Galvin, Dr. Paul Arnston, and Dr. Maria Chapman, will explore how families facing a child's cancer diagnosis decide whether or not to participate in the ovarian cryopreservation clinical trial and the role that others, such as healthcare practitioners and religious counsel, play in this decision. The aim of this research is to understand how families facing a child's medical crisis make healthcare decisions and to develop a shared decision-making model aimed at informed choice. Project #4, under the direction of Dr. Karrie Snyder, will explore how adult women with breast cancer share their concerns regarding infertility with their physician, how they arrive at treatment decisions, and the impact of possible infertility on their lives and relationships after cancer, with special attention being paid to issues of racial/ethnic and socioeconomic diversity in patient's concerns and survivorship experiences. Project #5, under the direction of Prof. Matthew J. Loscalzo, will be a large-scale survey of cancer patients' concerns and treatment decisions and a comparison of these by key social characteristics including gender, race/ethnicity, socioeconomic status/and family status.

R01D的目标是在社会和生物医学科学的界面上推进学术，这将促进和扩展我们将新兴的肿瘤生育技术从替补席转移到床边的能力。具体地说，全面检查癌症患者对生育能力的担忧，以及患者如何，与他们的家人和医生一起，做出与生育相关的医疗决定，并了解在癌症诊断时围绕这些决定的社会、法律和伦理因素。建议数研究议程由五个经验性项目组成，并促进了医疗决策的三元模型患者、家庭成员(包括父母和伴侣)和医疗保健的作用供应商将接受检查。此外，拟议的研究议程利用三角方法论定性和定量项目将探索不孕不育和癌症和将包括调查工具、深度访谈和焦点小组；几个项目将将混合方法纳入各自的研究计划。项目#1，在 Linda Emanuel博士、Laurie Zoloth博士和Dorothy Roberts教授的指导将着眼于伦理和法律围绕癌症患者使用生殖技术的问题，特别强调对儿科患者及其家人的影响。项目2，在大卫·德拉诺夫博士的领导下，安德鲁·斯菲卡斯博士和查尔斯·班尼特博士是对年轻成年女性如何患上癌症的经济学分析癌症权衡了可能的不孕不育和保留生育能力治疗的成本和好处。项目3，在凯瑟琳·加尔文博士的指导下，保罗·阿恩斯顿博士和玛丽亚·查普曼博士将探索面临儿童癌症诊断的家庭决定是否参与卵巢冷冻保存临床试验以及其他人，如医疗从业者和宗教顾问在其中所扮演的角色决定。这项研究的目的是了解面临儿童医疗危机的家庭是如何卫生保健决策，并开发旨在进行知情选择的共享决策模式。项目#4，在Karrie Snyder博士的指导下，将探索患有乳腺癌的成年女性如何分享她们的他们的医生对不孕不育的担忧，他们如何做出治疗决定，以及癌症后可能的不孕不育对他们的生活和关系的影响，特别关注以下问题患者关心的问题和生存经历中的种族/民族和社会经济多样性。项目5，在Matthew J.Loscalzo教授的指导下，将对癌症患者关注的问题进行大规模调查和治疗决定，并通过包括性别在内的关键社会特征对它们进行比较，种族/族裔、社会经济地位/和家庭地位。