Intervention to Prevent Delayed Diagnosis of Oral Cancer

描述（由申请人提供）：候选人：Alvin G。Wee，BDS，MS，MPH对临床研究的学术生涯表现出强烈的承诺。这个K23应用程序的目标是在临床研究中提供指导指导，因为他从事的职业发展活动由研究计划补充。这将完成他向成为一名独立研究人员的过渡，专注于口腔癌的预防和早期发现。建议的职业发展活动包括与导师和顾问的预定联系，以及参加相关的研讨会/科学会议，学术课程和暑期课程。工作环境：俄亥俄州州立大学（OSU）健康科学校区提供了丰富的环境，有广泛的研究活动，建立导师和必要的物理资源，以支持本申请的活动。校园的相关组成部分，以这个应用程序包括牙科学院，综合癌症中心（CCC），公共卫生学院，耳鼻喉科，心理学和内科的部门。所有的导师和顾问都在现场，在各自的领域有充足的资金，并有指导临床研究人员的经验。主要导师将由E。D. Paskett，the Marion N.公共卫生学院癌症研究罗利教授和俄勒冈州立大学CCC人口科学副主任。其他将提供指导的共同导师和顾问对研究计划具有相关的专业知识。研究：这项建议的一般假设是，有患口腔癌风险的群体更有可能看到其他医疗保健专业人员的医疗问题，而不是牙医。该研究计划的目的是开发和测试基于网络的教育干预的可行性，为初级保健医生，以促进口腔癌的早期发现（目标#3）。关于患者相关决定因素（目标1）和与口腔癌晚期诊断相关的医疗保健相关决定因素（目标2）的信息都将有助于开发基于网络的教育干预。相关性：这一应用与《2010年健康人》的两个目标有关：（1）增加在最早阶段检测到的口腔和咽癌的比例，从基线的35%增加到目标的50%，及（2）增加报告在过去12个月内曾接受口腔及咽癌检查的成年人比例，达到20%的目标。

DESCRIPTION (provided by applicant): Candidate: Alvin G. Wee, BDS, MS, MPH has shown strong commitment to an academic career in clinical research. The goal of this K23 application is to provide mentored guidance in clinical research as he engages in career development activities complemented by a research program. This will finalize his transition toward becoming an independent researcher focusing on the prevention and early detection of oral cancer. Proposed career development activities include scheduled contacts with mentors and consultants and attending relevant seminars/scientific meetings, academic courses and summer programs. Environment: Ohio State University (OSU) Health Science Campus provides a rich environment with extensive research activities, established mentors and physical resources necessary to support the activities of this application. Relevant components of the Campus to this application includes the College of Dentistry, Comprehensive Cancer Center (CCC), School of Public Health, and Departments of Otolaryngology, Psychology and Internal Medicine. All mentors and consultants are onsite, are well funded in their fields, and have experience in mentoring clinical researchers. Primary mentorship will be provided by E. D. Paskett, the Marion N. Rowley Professor of Cancer Research at the School of Public Health and Associate Director of Population Sciences, OSU CCC. Other co-mentors and consultants that will provide guidance have relevant expertise to the research program. RESEARCH: The general hypothesis of this proposal is that groups at risk for developing oral cancer are more likely to see other healthcare professionals for their medical problems than dentists. The objective of the research program is to develop and test the feasibility of a web-based educational intervention for primary care physicians to promote early detection of oral cancer (Aim #3). Information obtained on patient-related determinants (Aim #1) and healthcare-related determinants relevant to late stage diagnosis of oral cancer (Aim #2) will both contribute to the development of the web-based educational intervention. RELEVANCE: This application is relevant to two objectives of the Healthy People 2010: (1) to increase the portion of oral and pharyngeal cancer that is detected at the earliest stage, from baseline of 35% to target of 50%, and (2) to increase the portion of adults who report having had an examination to detect oral and pharyngeal cancer in the past 12 months from the 13% baseline to the target of 20%.