Reagent Research Support

试剂研究支持

• 批准号: 7789114
• 负责人: RONALD BROWN
• 金额: $ 316.45万
• 依托单位: QUALITY BIOLOGICAL, INC.
• 依托单位国家: 美国
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-04-14 至 2011-04-13
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7789114
• 关键词: Reagent; Research; Support

1)Produce , purify, and test reagents for HIV vaccine research, such as viral proteins , peptides, virus stocks, monoclonal and polyclonal antibodies, topical microbicides, vaccine adjuvants and cytokines, and any additional reagents deemed necessary for the DAIDS vaccine program, 2) Capability for genetic cloning and sequencing, 3) Capability of producing and testing unique and customized HIV reagents at the request of the program, including preparing and/or producing soluble proteins, expression vectors, and gene products (including experimental AIDS vaccines) under current Good Laboratory Practice (cGLP) or Good Manufacturing Practice (cGMP) as appropriate for their intended use, and preparing and/or producing these in large-scale production lots

1)生产、纯化和测试用于HIV疫苗研究的试剂，如病毒蛋白、肽、病毒原液、单克隆和多克隆抗体、局部杀微生物剂、疫苗佐剂和细胞因子，以及DAIDS疫苗计划所需的任何其他试剂， 2)基因克隆和测序能力， 3)能够根据项目要求生产和检测独特和定制的HIV试剂，包括根据现行药物非临床研究质量管理规范（GLP）或药物生产质量管理规范（cGMP）制备和/或生产适用于其预期用途的可溶性蛋白质、表达载体和基因产品（包括实验性艾滋病疫苗），并以大规模生产批次制备和/或生产这些试剂