Biological Bases of Nervous Systems Disorders

描述(由申请人提供)： 这项申请是德雷克塞尔大学医学院正在进行的专注于神经系统疾病生物学基础的博士后培训计划的竞争性更新。该计划的目标是为学员提供所需的观点和技能，为他们在神经生物学研究领域的独立职业生涯做好准备。我们请求支持四名研究员，他们将拥有博士或医学博士学位。该计划将为基础和临床科学家的实验室中的多学科研究项目提供机会，并接触到各种实验和临床问题。该方案涉及面广，由四个相互高度互动的重点小组组成。第一组侧重于细胞和发育神经生物学；第二组侧重于系统和行为神经生物学；第三组侧重于脊髓和再生；第四组侧重于神经工程。共有10名高级教职员工将担任初级培训教师。另有8名初级教员也将在高级教员的监督下担任培训员。所有参与的教员，无论是高级的还是初级的，都是由NIH资助的，出版得很好，并积极参与研究和培训。此外，我们大学系统内的三家不同医院有大量的临床研究人员，他们将参与研究员的培训。除了学员和导师之间的主要关系外，还有许多活动确保广泛接触现代神经生物学的问题和技术。其中包括围绕四个重点小组开发的课程、期刊俱乐部和研讨会、研究会议和共享实验室设施。将通过研究会议和研讨会，定期正式审查和不断监测每个受训人员的进展情况。这一过程确保了对计划中可用的各种学科和观点的完全访问。

DESCRIPTION (provided by applicant): This application is the competing renewal for the ongoing postdoctoral training program at Drexel University College of Medicine focused on the biological bases of nervous system disorders. The objective of the program is to provide trainees with the perspectives and skills needed to prepare them for independent careers in neurobiological research. We request support for four fellows, who will have either the Ph.D. or M.D. degree. The program will provide opportunities for multidisciplinary research projects in the laboratories of both basic and clinical scientists and exposure to a wide variety of experimental and clinical issues. The program is broadly-based, and consists of four focal groups that are highly interactive with one another. The first group focuses on cellular and developmental neurobiology; the second group on systems and behavioral neurobiology, the third group on spinal cord and regeneration; and the fourth group on neuroengineering. There are a total of 10 senior level faculty members who will act as the primary training faculty. There are an additional 8 junior level faculty members who will also act as trainers, under the supervision of the senior faculty. The entire participating faculty, both senior and junior, is funded by the NIH, well published, and active in both research and training. In addition, there is an abundance of clinical researchers at three different hospitals within our university system who will participate in the training of the fellows. In addition to the primary relationship between a trainee and the mentor, there are a number of activities that ensure a broad exposure to the issues and techniques of modern neurobiology. These include courses developed around the four focal groups, journal clubs and seminars, research conferences and shared laboratory facilities. The progress of each trainee will be formally reviewed regularly and monitored constantly, through research meetings and seminars. This process assures full access to the various disciplines and perspectives available in the program.