Training Program on Innovative Approaches to Spinal Cord Injury

项目概要/摘要 脊髓损伤（SCI）是一种毁灭性的疾病，影响着大约25万美国人，有17,700例新发病例 每年花费超过两百万美元对于这些病人， 改善他们的前景，甚至部分恢复或改善症状，负面影响他们的 生活质量SCI研究继续向前发展，但需要更大胆，更创新的突破，如果 这些努力将转化为改善症状、减轻疼痛和恢复功能的疗法。作为 NIH主办的SCI-2020会议强调，迫切需要新一代的SCI研究人员， 一个是在所有需要的背景和该领域的历史，同时也装备， 通过与来自世界各地的科学家进行强有力的合作互动，将新技术和见解带入该领域。 其他领域德雷克塞尔大学医学院是马里恩·默里脊髓研究中心的所在地， 该组织在教育和培训的同时，也在推动SCI领域的发展， 博士生们把这个领域向前推进。在中心内是德雷克塞尔SCI培训计划，其中包括 资金充足和充满活力的研究人员从许多不同的角度研究SCI，并指导学员 许多不同的方法。其中包括工程学、电生理学、细胞移植、康复和 他人该中心与来自其他领域的德雷克塞尔研究人员进行了广泛的多学科合作，其中许多 参加SCI培训计划的人员。该中心设在神经生物学系内 和解剖学，与神经科学研究生课程的学生。SCI学生暴露 众多的培训经验，包括但不限于什么神经科学研究生课程 提供，具有灵活性，欢迎来自其他研究生课程的学生转入该计划， 进行SCI相关研究。该计划已经存在了30多年，并取得了持续的成功。 学生获得F31资金，以资助他们的高年级，然后在他们的职业生涯中取得成功后， 完成程序。该计划的T32资金将使研究和数量的扩展成为可能。 培训人员，从而改善了SCI患者的前景，对他们来说，治疗仍然遥遥无期。

PROJECT SUMMARY/ABSTRACT Spinal cord injury (SCI) is a devastating condition that affects about 250,000 Americans with 17,700 new cases annually costing upwards of $2 million each. There is very little that can be done to treat these patients that improves their prospects for even partial recovery or the amelioration of symptoms that negatively impact their quality of life. SCI research continues to advance, but bolder and more innovative breakthroughs are needed, if the efforts are to translate into therapies that improve symptoms, alleviate pain, and restore functionality. As highlighted by the NIH-hosted SCI-2020 meeting, a new generation of SCI researchers is desperately needed, one that is thoroughly educated in all of the needed background and history of the field while also equipped to bring new technologies and insights into the field through strong collaborative interactions with scientists from other fields. Drexel University College of Medicine is home to the Marion Murray Spinal Cord Research Center, which has over three decades of history advancing the SCI field while simultaneously educating and training doctoral students to take the field forward. Within the Center is the Drexel SCI Training Program, which consists of well-funded and vibrant investigators who study SCI from many different perspectives, and mentor trainees in many different approaches. These include engineering, electrophysiology, cell transplantation, rehabilitation and others. The center has extensive multidisciplinary collaborations with Drexel investigators from other fields, many of whom are involved in the SCI Training Program. The Center is based within the Department of Neurobiology and Anatomy, with the students affiliated with the Neuroscience Graduate Program. SCI students are exposed to a multitude of training experiences, including but not limited to what the Neuroscience Graduate Program offers, with flexibility that welcomes students from other graduate programs to transfer into the program in order to conduct SCI-relevant research. The program has existed for over thirty years, with consistent success of the students securing F31 funding to fund their senior years, and then achieving success in their careers after completing the program. T32 funding for the program will enable expansion of the research and the number of trainees, thus improving the prospects of SCI patients, for whom treatments have remained elusive for too long.