Training Program on Innovative Approaches to Spinal Cord Injury

项目摘要/摘要 脊髓损伤(SCI)是一种毁灭性的疾病，影响着大约25万美国人和17700个新病例 每年每台花费超过200万美元。对于这些患者，我们几乎无能为力 改善他们的前景，即使是部分恢复或改善对他们的 生活质量。SCI研究继续向前推进，但需要更大胆和更具创新性的突破，如果 这些努力是为了转化为改善症状、减轻疼痛和恢复功能的疗法。AS 由NIH主办的SCI-2020会议强调，迫切需要新一代SCI研究人员， 受过该领域所有所需背景和历史的全面教育，同时也具备 通过与科学家的强大协作互动，将新技术和见解带入该领域 其他字段。德雷克塞尔大学医学院是马里恩·默里脊髓研究中心的所在地， 有三十多年的历史，在推进SCI领域的同时，教育和培训并存 博士生把这一领域推向前进。该中心的内部是德雷克塞尔SCI培训计划，该计划包括 由资金雄厚、充满活力的研究人员组成，他们从许多不同的角度研究SCI，并在 许多不同的方法。这些包括工程学、电生理学、细胞移植、康复和 其他。该中心与来自其他领域的Drexel调查人员进行了广泛的多学科合作，其中许多 其中一些人参与了SCI培训计划。该中心设在神经生物学系内 和解剖学，与神经科学研究生项目的学生一起。SCI学生被曝光 一系列培训经验，包括但不限于神经科学研究生项目 提供优惠，灵活欢迎其他研究生项目的学生按顺序转到该项目 开展与脊髓损伤相关的研究。该计划已经存在了30多年，并不断取得成功 学生获得F31资助以资助他们的大四，然后在他们的职业生涯中取得成功 正在完成程序。为该计划提供的T32资金将使研究和数量得以扩大 受训人员，从而改善了脊髓损伤患者的前景，对他们来说，治疗太久了。

PROJECT SUMMARY/ABSTRACT Spinal cord injury (SCI) is a devastating condition that affects about 250,000 Americans with 17,700 new cases annually costing upwards of $2 million each. There is very little that can be done to treat these patients that improves their prospects for even partial recovery or the amelioration of symptoms that negatively impact their quality of life. SCI research continues to advance, but bolder and more innovative breakthroughs are needed, if the efforts are to translate into therapies that improve symptoms, alleviate pain, and restore functionality. As highlighted by the NIH-hosted SCI-2020 meeting, a new generation of SCI researchers is desperately needed, one that is thoroughly educated in all of the needed background and history of the field while also equipped to bring new technologies and insights into the field through strong collaborative interactions with scientists from other fields. Drexel University College of Medicine is home to the Marion Murray Spinal Cord Research Center, which has over three decades of history advancing the SCI field while simultaneously educating and training doctoral students to take the field forward. Within the Center is the Drexel SCI Training Program, which consists of well-funded and vibrant investigators who study SCI from many different perspectives, and mentor trainees in many different approaches. These include engineering, electrophysiology, cell transplantation, rehabilitation and others. The center has extensive multidisciplinary collaborations with Drexel investigators from other fields, many of whom are involved in the SCI Training Program. The Center is based within the Department of Neurobiology and Anatomy, with the students affiliated with the Neuroscience Graduate Program. SCI students are exposed to a multitude of training experiences, including but not limited to what the Neuroscience Graduate Program offers, with flexibility that welcomes students from other graduate programs to transfer into the program in order to conduct SCI-relevant research. The program has existed for over thirty years, with consistent success of the students securing F31 funding to fund their senior years, and then achieving success in their careers after completing the program. T32 funding for the program will enable expansion of the research and the number of trainees, thus improving the prospects of SCI patients, for whom treatments have remained elusive for too long.