Humanisation and pre-clinical validation of a therapeutic anti-cancer antibody

治疗性抗癌抗体的人源化和临床前验证

• 批准号: nhmrc : GNT1093304
• 负责人: Dr Peter Janes
• 金额: $ 67.82万
• 依托单位: La Trobe University
• 依托单位国家: 澳大利亚
• 项目类别: Development Grants
• 财政年份: 2015
• 资助国家: 澳大利亚
• 起止时间: 2015-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/humanisation-pre-clinical-cancer-antibody/1345911
• 关键词: Humanisation; pre; clinical; validation; therapeutic

This grant will develop a novel antibody against a protease expressed on cancer cells. Preclinical studies, and antibody humanisation, will be performed. This project will also provide vital information on optimal therapeutic approaches with the antibody that can be ultimately taken into human trials.

这项资助将开发一种针对癌细胞上表达的蛋白酶的新型抗体。将进行临床前研究和抗体人源化。该项目还将提供有关最终可用于人体试验的抗体的最佳治疗方法的重要信息。