HUMAN TISSUE AND ORGAN RESOURCE FOR RESEARCH

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 描述(由申请人提供)： NDRI的人类组织和器官研究(HTOR)计划专门致力于获取和提供用于研究目的的人体组织。这些组织和器官是HTOR服务的绝大多数研究项目所必需的，该计划显然与促进人类健康有关。HTOR的长期目标是增加可用于研究的人体研究组织的数量、多样性和质量。组织的收集、准备和保存必须按照研究人员指定的方案进行，才能使材料对科学家有用。收购这些材料需要一个广泛的全国性采购网站网络，如医院病理学和外科服务、眼科和组织库以及器官采购组织。HTOR独特的系统确保为定制方案采购的组织以及时的方式交付到适当的研究目的地。运送给调查人员的组织的数量、质量和多样性取决于三个关键变量：与HTOR合作的来源的数量和类型、HTOR的内部系统以及HTOR从研究人员收到的研究请求的数量和类型。拟议资助期的具体目标侧重于加强HTOR计划的这三个部门(来源、信息系统和研究人员)。HTOR将致力于提高现有来源的能力，并增加新的来源，以增加组织的数量和多样性(特定目标1/来源)；升级HTOR的内部系统(计算机硬件、软件和数据管理)，以改进数据捕获和分析，并升级HTOR网站，以增加来源和研究人员对HTOR资源的访问(特定目标2/系统)；并与研究界密切合作，满足对人体研究组织的现有和新出现的需求(特定目标3/研究人员)。此外，HTOR将继续实施一项专门的计划，以获取和分发HIV阳性组织(具体目标4)，这一目标也与HTOR的长期目标一致。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. DESCRIPTION (provided by applicant): The Human Tissues and Organs for Research (HTOR) program of the NDRI is dedicated solely to accessing and providing human tissues for research purposes. These tissues and organs are essential for the great majority of research projects served by HTOR and the program is clearly relevant to advancing human health. HTOR's long-term objective is to increase the quantity, diversity, and quality of human research tissues available for research. The collection, preparation, and preservation of the tissues must be performed according to researcher-specified protocols for the materials to be useful to scientists. The acquisition of these materials requires an extensive national network of acquisition sites such as hospital pathology and surgical services, eye and tissue banks, and Organ Procurement Organizations. HTOR's unique systems ensure that tissues procured for customized protocols are delivered in a timely manner to the appropriate research destinations. The quantity, quality and diversity of tissues shipped to investigators is a function of three critical variables: the number and types of sources working with HTOR, the internal systems of HTOR, and the number and types of research requests that HTOR receives from researchers. The specific aims of the proposed funding period focus on strengthening these three arms of the HTOR program (sources, information systems, and researchers). HTOR will work to increase the capabilities of existing sources and add new sources to increase tissue quantity and diversity (Specific Aim 1/Sources); upgrade HTOR's internal systems (computer hardware, software, and data management) to improve data capture and analysis, and upgrade the HTOR Web Site to increase Source and Researcher access to HTOR resources (Specific Aim 2/Systems); and work closely with the research community to fulfill existing and emerging needs for human research tissue (Specific Aim 3/Researchers). In addition, HTOR will continue a specialized program for procuring and distributing HIV positive tissues (Specific Aim 4), a goal that is also consistent with HTOR's long-term objective.