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Renal Cellular Remodeling Following Ureteral Obstruction

Renal Cellular Remodeling Following Ureteral Obstruction
输尿管梗阻后的肾细胞重塑
批准号：
7501080
负责人：
ROBERT L. CHEVALIER
金额：
$22.63万
依托单位：
UNIVERSITY OF VIRGINIA
依托单位国家：
美国
项目类别：
财政年份：
2007
资助国家：
美国
项目状态：
已结题
起止时间：
2007-07-01 至 2008-06-30
来源：
https://reporter.nih.gov/project-details/7501080
关键词：
AGTR2 geneAdultAdverse effectsAngiotensin IAngiotensin IIAngiotensin ReceptorAngiotensinsAnti-Inflammatory AgentsAnti-inflammatoryApoptosisApoptoticAtrophicBiological MarkersBlast CellCCL2 geneCell DeathCell ProliferationCellsCessation of lifeChemotactic FactorsChildChronicClinical TrialsCollaborationsDefensinsDevelopmentDiagnosisDiseaseDiureticsDysplasiaEarly DiagnosisEpidermal Growth FactorEvolutionExcretory functionFetal KidneyFetal UltrasonographyFibroblastsFibrosisGenerationsGenesGoalsGrowthGrowth and Development functionHistocytochemistryHumanInfantInflammationInflammatoryInflammatory InfiltrateInjection of therapeutic agentInjuryInterventionKidneyKidney DiseasesKidney FailureKnockout MiceLeadLesionLeucocytic infiltrateLong-Term EffectsMacrophage ActivationMeasuresMediator of activation proteinModelingMusNecrosisNeonatalNephronsNitric OxideNitric Oxide SynthaseObstructionOperative Surgical ProceduresOutcomePathway interactionsPeptidesPilot ProjectsPlayPregnancyProcessProductionPropertyRattusReceptor InhibitionRegulationRenin-Angiotensin SystemResearch PersonnelRoleSchemeSecond Pregnancy TrimesterSeveritiesSolidSonic Hedgehog PathwayTestingTherapeuticTimeTransforming Growth Factor betaTransforming Growth FactorsTubular formationType 2 Angiotensin II ReceptorUltrasonographyUncertaintyUreteral obstructionUreteropelvic junction obstructionWeekWild Type Mousecell injurycell typecytokinedayhuman NOS2A proteinhuman NOS3 proteinhuman TGFB1 proteinimprovedinfant outcomeinterstitialkidney visualizationmacrophagemature animalmonocytenephrogenesisneutralizing antibodynovel diagnosticsosteopontinoutcome forecastpostnatalprenatalprospectivereceptorresponseurinaryurinary tract obstruction

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