Scholars' Program in the Genetics and Genomics of Lung Diseases

描述（由申请人提供）： 该倡议的目标是增加致力于肺部疾病研究的研究人员的数量，使这些新的研究人员具备遗传学和基因组学研究的必要技能，以研究复杂的遗传疾病。我们的方法，以满足这一举措的意图是培养学者在基因组学研究中使用人类遗传学中心和肺部，重症监护和免疫疾病部门的综合设施，结合两个已经建立的硕士学位课程之一（健康科学研究或分子医学），其中包括一年的研究。本课程将补充额外的实验室轮换，以培养遗传学和基因组学研究的基础学者。最后，所有学者将在两位导师的指导下参与职业发展和积极研究，目标是在同行评审的期刊上发表文章，并发展独立的科学研究技能。我们有一个强大的综合人类基因组学中心，资金充足，重点是呼吸遗传学，主要是哮喘遗传学，其次是COPD遗传学。基因组学中心内的十名教师在肺科有他们的主要学术任命。目前，博士后研究员在临床培训期间有一年的全职研究。这笔培训补助金将允许这些肺科受训人员申请基因组学和肺科医学的全职研究，同时在两到三年内完成硕士学位。因此，该计划可以与目前的肺部培训计划相结合，以支持额外的研究培训，以发展成为独立医生科学家所需的技能。其他人可以进入这个程序与博士重点呼吸研究，并将能够开发基因组学研究的技能，从而促进研究方向和职业发展。 (End摘要）

DESCRIPTION (provided by applicant): The goal of this initiative is to increase the number of investigators committed to research in pulmonary diseases by equipping these new investigators with the necessary skills for genetics and genomics research to study complex genetic disease. Our approach to meeting the intent of this initiative is train Scholars in genomics research using the integrated facilities of the Center for Human Genetics and the Division of Pulmonary, Critical Care and Immunologic Diseases in conjunction with one of two already established Master's Degree Programs (Health Sciences Research or Molecular Medicine) which includes a year of research. This curriculum will be supplemented with additional laboratory rotations to train Scholars in the fundamentals of genetics and genomics research. Finally, all Scholars will participate in career development and active research under the mentorship of two faculty supervisors with the goal of publications in peer reviewed journals and the development of independent scientific research skills. We have a strong integrated Center for Human Genomics which is well-funded with a strong emphasis on respiratory genetics, primarily genetics of asthma and, secondary, genetics of COPD. Ten faculty within the Genomics Center have their primary academic appointment in the Pulmonary Section. Currently, postdoctoral fellows have one year of full time research during their clinical training. This training grant would permit these pulmonary trainees to apply for full time research in genomics and pulmonary medicine while completing a masters degree over a two to three year period. Thus, the program can be integrated with the current pulmonary training program to support an additional research training to develop the skills necessary to become an independent physician scientist. Others may enter this program with a PhD with emphasis on respiratory research and will be able to develop skills in genomics research, thus, facilitating research directions and career development. (End of Abstract)