Scholars' Program in the Genetics and Genomics of Lung Diseases

描述(由申请人提供)： 这项倡议的目标是通过为这些新的研究人员配备遗传学和基因组学研究的必要技能，以研究复杂的遗传病，从而增加致力于肺部疾病研究的研究人员的数量。我们实现这一计划意图的方法是利用人类遗传学中心和肺、重症护理和免疫疾病部门的综合设施，结合已经建立的两个硕士学位项目(健康科学研究或分子医学)之一，培训学者进行基因组研究，其中包括一年的研究。本课程将辅以额外的实验室轮换，以训练学者掌握遗传学和基因组研究的基本知识。最后，所有学者将在两名教师导师的指导下参与职业发展和积极研究，目标是在同行评议的期刊上发表文章，并发展独立的科学研究技能。我们有一个强大的综合人类基因组学中心，该中心资金充足，非常重视呼吸道遗传学，主要是哮喘的遗传学，其次是COPD的遗传学。基因组学中心的十名教员的主要学术任命是在肺科。目前，博士后研究员在临床培训期间有一年的全职研究。这笔培训补助金将允许这些肺部受训人员申请全日制基因组学和肺部医学研究，同时在两到三年内完成硕士学位。因此，该计划可以与当前的肺部培训计划相结合，以支持额外的研究培训，以发展成为独立内科科学家所需的技能。其他人可能会以呼吸系统研究为重点的博士学位进入这个项目，并将能够发展基因组研究的技能，从而促进研究方向和职业发展。 (摘要结束)

DESCRIPTION (provided by applicant): The goal of this initiative is to increase the number of investigators committed to research in pulmonary diseases by equipping these new investigators with the necessary skills for genetics and genomics research to study complex genetic disease. Our approach to meeting the intent of this initiative is train Scholars in genomics research using the integrated facilities of the Center for Human Genetics and the Division of Pulmonary, Critical Care and Immunologic Diseases in conjunction with one of two already established Master's Degree Programs (Health Sciences Research or Molecular Medicine) which includes a year of research. This curriculum will be supplemented with additional laboratory rotations to train Scholars in the fundamentals of genetics and genomics research. Finally, all Scholars will participate in career development and active research under the mentorship of two faculty supervisors with the goal of publications in peer reviewed journals and the development of independent scientific research skills. We have a strong integrated Center for Human Genomics which is well-funded with a strong emphasis on respiratory genetics, primarily genetics of asthma and, secondary, genetics of COPD. Ten faculty within the Genomics Center have their primary academic appointment in the Pulmonary Section. Currently, postdoctoral fellows have one year of full time research during their clinical training. This training grant would permit these pulmonary trainees to apply for full time research in genomics and pulmonary medicine while completing a masters degree over a two to three year period. Thus, the program can be integrated with the current pulmonary training program to support an additional research training to develop the skills necessary to become an independent physician scientist. Others may enter this program with a PhD with emphasis on respiratory research and will be able to develop skills in genomics research, thus, facilitating research directions and career development. (End of Abstract)